4156-59-6 Usage
Description
3,4,5-Trimethoxybenzo-amidite hydrochloride is a chemical compound that serves as a crucial building block in organic chemistry. It features a benzene ring with three methoxy groups and an amide functional group, with the hydrochloride salt form enhancing its solubility and stability for easier handling and storage. Widely utilized in the pharmaceutical and biotechnology industries, this compound plays a significant role in the production of various drugs and biologically active compounds.
Uses
Used in Pharmaceutical Industry:
3,4,5-Trimethoxybenzo-amidite hydrochloride is used as a reagent for the synthesis of organic molecules, particularly in the production of peptides and oligonucleotides. Its role in creating complex molecular structures makes it invaluable for developing new drugs and therapies.
Used in Biotechnology Industry:
In the biotechnology sector, 3,4,5-Trimethoxybenzo-amidite hydrochloride is employed as a key component in the development of biologically active compounds. Its unique structure and properties contribute to the creation of innovative solutions for various applications, including diagnostics, therapeutics, and research tools.
Check Digit Verification of cas no
The CAS Registry Mumber 4156-59-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,5 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4156-59:
(6*4)+(5*1)+(4*5)+(3*6)+(2*5)+(1*9)=86
86 % 10 = 6
So 4156-59-6 is a valid CAS Registry Number.
4156-59-6Relevant articles and documents
Facile synthesis of 3,5-diaryl-1,2,4-triazoles via copper-catalyzed domino nucleophilic substitution/oxidative cyclization using amidines or imidates as substrates
Sudheendran, Kavitha,Schmidt, Dietmar,Frey, Wolfgang,Conrad, Jürgen,Beifuss, Uwe
, p. 1635 - 1645 (2014/02/14)
Two methods for the synthesis of 3,5-diaryl-1,2,4-triazoles, both domino reactions, are reported. The first procedure, the Cu(OTf)2-catalyzed reaction between two amidines using NaHCO3 as a base, 1,10-phenanthroline as an additive and K3[Fe(CN)6]/ atmospheric oxygen as the oxidant, delivers 3,5-diaryl-1,2,4-triazoles with yields up to 68%. The second procedure for the synthesis of 3,5-diaryl-1,2,4- triazoles with yields up to 64% rests on the Cu(OTf)2-catalyzed reaction between two imidates and ammonium carbonate. This method features the formation of three bonds in a single synthetic step.
