41723-91-5Relevant articles and documents
PROCESS FOR THE PREPARATION OF F-SERIES PROSTAGLANDINS
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Page/Page column 47-49, (2011/05/05)
A process for the synthesis and purification of F-series prostaglandin compounds and synthetic intermediates used to prepare them. The synthetic intermediates are solid and may be purified by precipitation and therefore may form the representative F-series prostaglandin compounds such as latanoprost, bimatoprost, fluprostenol, cloprostenol, and substituted analogs therefrom in highly pure forms.
PROSTANOIDS. LIX. ENANTIODIVERGENT SYNTHESIS OF (+)- AND (-)-9,11-DIDESOXY-9,11-ETHANO ANALOGS OF PROSTAGLANDIN ENDOPEROXIDE AND THEIR C15-DIASTEREOMERS
Miftakhov, M. S.,Valeev, F. A.,Gaisina, I. N.,Shitikova, O. V.,Sultanmuratova, V. R.,Tolstikov, G. A.
, p. 933 - 943 (2007/10/02)
Schemes are described for the transformation of (-)-(1S,2S,3S,6R,7R,9R)-10,12-dioxatetracyclo3,6.02,7>tridecan-8-one obtained by the hydrogenation of the endo adduct synthesized in the Diels-Alder reaction from levoglucosenon
Prostaglandins. 2. Synthesis of Prostaglandin F2α in Optically Active Form from Chiral Precursors
Johnson, Francis,Paul, K.G.,Favara, Duccio,Ciabatti, Romeo,Guzzi, Umberto
, p. 2190 - 2198 (2007/10/02)
A synthetic route to optically active prostaglandins is described which use chiral starting materials.Acylation of the bis(magnesiobromide) salt of methyl hemimalonate with (S)-(-)-2-acetoxysuccinyl chloride led to unstable dimethyl (S)-4-acetoxy-3,6-diox