41727-18-8Relevant articles and documents
Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers
Chen, Song,Chen, Yue-Gang,Gao, Pei-Sen,Liu, Dong,Ma, Hong-Xing,Mei, Tian-Sheng,Qiu, Hui,Shuai, Bin,Wang, Yun-Zhao
supporting information, p. 9872 - 9878 (2020/06/27)
A scalable enantioselective nickel-catalyzed electrochemical reductive homocoupling of aryl bromides has been developed, affording enantioenriched axially chiral biaryls in good yield under mild conditions using electricity as a reductant in an undivided cell. Common metal reductants such as Mn or Zn powder resulted in significantly lower yields in the absence of electric current under otherwise identical conditions, underscoring the enhanced reactivity provided by the combination of transition metal catalysis and electrochemistry.
Manganese-Catalyzed Direct Nucleophilic C(sp2)-H Addition to Aldehydes and Nitriles
Zhou, Bingwei,Hu, Yuanyuan,Wang, Congyang
supporting information, p. 13659 - 13663 (2015/11/16)
Herein, a manganese-catalyzed nucleophilic addition of inert C(sp2)-H bonds to aldehydes and nitriles is disclosed by virtue of a dual activation strategy. The reactions feature mild reaction conditions, excellent regio- and stereoselectivity, and a wide substrate scope, which includes both aromatic and olefinic C-H bonds, as well as a large variety of aldehydes and nitriles. Moreover, mechanistic studies shed light on possible catalytic cycles.
Lewis Acid Complexed Heteroatom Carbanions; Synthesis of some α-Pyridyl Alcohols
Kessar, Satinder V.,Singh, Paramjit,Singh, Kamal Nain,Dutt, Mahesh
, p. 570 - 571 (2007/10/02)
Metallation of BF3-pyridine complex with lithium tetramethylpiperidide (LTMP) in ether at -78 deg C, followed by reaction with carbonyl compounds, affords α-pyridyl alcohols in good yields.
