417719-47-2

Basic information

• Product Name: 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(propylamino)carbonyl]amino]phenoxy]-7-methoxy-
• CAS NO: 417719-47-2
• Molecular Formula: C21H21ClN4O4
• Molecular Weight: 428.875
• Mol File: 417719-47-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(propylamino)carbonyl]amino]phenoxy]-7-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(propylamino)carbonyl]amino]phenoxy]-7-methoxy-(417719-47-2)
• EPA Substance Registry System: 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(propylamino)carbonyl]amino]phenoxy]-7-methoxy-(417719-47-2)

Safety Data

• Hazardous Substances Data: 417719-47-2(Hazardous Substances Data)

Upstream product

• 107-10-8 propylamine 
• 417722-95-3 {4-[(6-carbamoyl-7-methoxy-4-quinolyl)oxy]-2-chlorophenyl}amino-carboxylic acid phenyl ester 

Relevant articles and documents

METHOD FOR ASSAY ON THE EFFECT OF VASCULARIZATION INHIBITOR

The present invention provides a method of predicting the antitumor effect of an angiogenesis inhibitor. It is possible to predict the antitumor effect of an angiogenesis inhibitor by evaluating the EGF dependency of a tumor cell for proliferation and/or survival and using the EGF dependency as an indicator. Since the antitumor effect of an angiogenesis inhibitor correlates with the EGF dependency of a tumor cell for proliferation and/or survival, the angiogenesis inhibitors is capable of producing excellent antitumor effect when combined with a substance having EGF inhibitory activity.