417722-95-3Relevant articles and documents
Preparation method of lenvatinib and preparation method of lenvatinib intermediate
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Paragraph 0130-0132; 0134-0139, (2021/07/01)
The invention discloses a preparation method of lenvatinib and a preparation method of a lenvatinib intermediate. The preparation method of an amide compound as shown in a formula II comprises the following step: in a solvent, carrying out amidation react
Synthesis method of lenvatinib and new intermediate
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, (2020/07/24)
The invention discloses a synthesis method of lenvatinib and a new intermediate. The method comprises the following steps: step 1, taking 4-amino-3-chlorophenol hydrochloride and 4-chloro-7-methoxy-6-amido quinoline as initial raw materials, and carrying
Preparation method of lenvatinib and its salts
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, (2019/06/30)
The invention discloses a preparation method of lenvatinib and its salts, wherein N-methylpyrrolidone is used as a reaction solvent in the step of condensation with phenyl chloroformate. The preparation method has the advantages that the danger is success