420-37-1 Usage
Description
Trimethyloxonium tetrafluoroborate, also known as (trimethyloxonium)tetrafluoroborate, is a trialkylated oxonium salt that exists as white to off-white crystals. It is widely utilized in various organic synthesis processes due to its unique chemical properties and reactivity.
Uses
1. Organic Synthesis:
Trimethyloxonium tetrafluoroborate is used as a methylation agent in organic synthesis, facilitating the transfer of a methyl group to other molecules, which is crucial for the formation of various organic compounds.
2. Activation of C-X Multiple Bonds:
In the field of organic chemistry, this compound acts as an activating agent for C-X multiple bonds, enhancing the reactivity of these bonds and enabling further chemical reactions.
3. Esterification of Polyfunctional Carboxylic Acids:
Trimethyloxonium tetrafluoroborate is employed in the esterification process of polyfunctional carboxylic acids, which is an essential step in the synthesis of various organic compounds and materials.
4. Polymerization Catalyst:
Trimethyloxonium tetrafluoroborate serves as a catalyst in the polymerization of cyclic sulfides and ethers, which are important processes in the production of polymers with specific properties and applications.
5. Beckmann Rearrangement:
Trimethyloxonium tetrafluoroborate is used in the Beckmann rearrangement of oximes, a significant chemical reaction that transforms oximes into amides, which are vital building blocks in the synthesis of various pharmaceuticals and organic compounds.
6. Reagent for Hydroxyl Group Methylation:
Recently, it has been used as a reagent for the methylation of hydroxyl groups in complex, multistep syntheses, such as the synthesis of spirastrellolide, a marine natural product with potential biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 420-37-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,2 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 420-37:
(5*4)+(4*2)+(3*0)+(2*3)+(1*7)=41
41 % 10 = 1
So 420-37-1 is a valid CAS Registry Number.
InChI:InChI=1/C3H9O.B.4FH/c1-4(2)3;;;;;/h1-3H3;;4*1H/q+1;+3;;;;/p-4
420-37-1Relevant articles and documents
Reactions of nitrilium salts with indole and pyrrole and their derivatives in the synthesis of imines, ketones and secondary amines
Giles, Robert G.,Heaney, Harry,Plater, M. John
, p. 7367 - 7385 (2015/08/24)
Abstract Reactions of N-methyl- and N-ethyl-nitrilium salts with indole and pyrrole and their derivatives yield imines or imine salts in good yields. The related imines are obtained from the salts after careful basification and hydrolysis of the imine salts or the imines by heating with aqueous base give the related ketones in good yields. Alternatively, the imine salts can be reduced using sodium borohydride in methanol to give the related secondary amines.
SUBSTITUTED IMIDAZOHETEROCYCLE DERIVATIVES
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Page/Page column 28-29, (2010/07/02)
The present invention provides substituted imidazoheterocycles having the general structure of formula (I), wherein Y is chosen from -O-, -OCRgRh-, -CRgRhO-, -CRgRh-, -(CRgRh)2-, -NRi-, -CRgRhNRi- and -NRiCRgRh-. Also provided are pharmaceutically acceptable salts, acid salts, hydrates, solvates and stereoisomers of the compounds of formula I. The compounds are useful as modulators of cannabinoid receptors and for the prophylaxis and treatment of cannabinoid receptor-associated diseases and conditions, such as pain, inflammation and pruritis.
Process for preparing derivatives of the taxoid family
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, (2008/06/13)
The present invention relates to a novel process for preparing dialkoxy derivatives of the taxoid family by direct alkylation of the two positions 7 and 10 of deacetylbaccatin or derivatives thereof which are esterified in position 13.
