51761-92-3

Basic information

• Product Name: (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester
• CAS NO: 51761-92-3
• Molecular Weight: 629.734
• Mol File: 51761-92-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester(51761-92-3)
• EPA Substance Registry System: (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester(51761-92-3)

Safety Data

• Hazardous Substances Data: 51761-92-3(Hazardous Substances Data)

Upstream product

• 7765-60-8 (6R)-3-acetoxymethyl-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 
• 51762-24-4 (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methylene-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]octane-2c-carboxylic acid benzhydryl ester 
• 54240-50-5 (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methylene-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]octane-2c-carboxylic acid 
• 420-37-1 trimethoxonium tetrafluoroborate 
• 54639-49-5 (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3,8-dioxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]octane-2ξ-carboxylic acid benzhydryl ester 
• 421-20-5 Methyl fluorosulfonate 
• 186581-53-3 diazomethane 

Downstream Products

• 51762-00-6 (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methoxy-5t,8-dioxo-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 
• 51762-17-5 cefroxadine 
• 54657-11-3 (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-3-ene-2ξ-carboxylic acid benzhydryl ester 
• 53116-66-8 (6R)-7t-((R)-2-tert-butoxycarbonylamino-2-phenyl-acetylamino)-3-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 

Relevant articles and documents

Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds

7β-amino-3-cephem-3-ol-4-carboxylic acid compounds of the formula STR1 wherein R1a represents hydrogen or an amino protective group R1A and R1B represents hydrogen or an acyl group Ac, or R1a and R1b together represent a bivalent amino protective group, R2 represents hydroxyl or a radical R2A which together with the carbonyl grouping --C(=O)-- forms a protected carboxyl group and R3 represents hydrogen, lower alkyl or a hydroxyl protective group, and 1-oxides or 3-cephem compounds of the formula IA, and the corresponding 2-cephem compounds are prepared in that a compound of the formula STR2 wherein R1a, R1b and R2A have the meanings mentioned under formula IA, R3o represents lower alkyl or a hydroxyl protective group and Y represents a group which is removed, is treated with a base; also comprised are intermediate products.