42038-75-5 Usage
Description
METHYL (S)-(-)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE is an organic compound with a complex structure, characterized by its chiral center and functional groups. It is a derivative of cyclopentene and heptanoic acid, featuring a hydroxyl group and a carbonyl group in its structure. METHYL (S)-(-)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE has potential applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
METHYL (S)-(-)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE is used as an intermediate in the synthesis of prostaglandins for the treatment of gastric and duodenal ulcers. Its unique structure allows for the development of pharmaceutical compounds that can target specific receptors and pathways involved in the healing process of ulcers.
Used in Chemical Synthesis:
In the field of chemical synthesis, METHYL (S)-(-)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE can be utilized as a building block for the creation of more complex molecules with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science. Its chiral center and functional groups make it a versatile starting material for the synthesis of enantiomerically pure compounds.
Used in Research and Development:
Due to its unique structure and potential applications, METHYL (S)-(-)-3-HYDROXY-5-OXO-1-CYCLOPENTENE-1-HEPTANOATE can be employed in research and development for the exploration of new chemical reactions, synthesis methods, and potential applications in various fields. Researchers can use this compound to study its reactivity, stability, and interactions with other molecules, leading to the discovery of new compounds and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 42038-75-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,0,3 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 42038-75:
(7*4)+(6*2)+(5*0)+(4*3)+(3*8)+(2*7)+(1*5)=95
95 % 10 = 5
So 42038-75-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H20O4/c1-17-13(16)7-5-3-2-4-6-10-8-11(14)9-12(10)15/h8,11,14H,2-7,9H2,1H3/t11-/m1/s1
42038-75-5Relevant articles and documents
An efficient synthesis of enantiomerically pure (1R,2S,5S)- and (1S,2R,5R)-rosaprostol methyl esters
Murcia, M. Carmen,De La Herran, Gabriela,Plumet, Joaquín,Csaky, Aurelio G.
, p. 1553 - 1556 (2008/02/05)
We report a concise synthesis of the enantiomerically pure 1,2-trans-1,5-cis-methyl esters of rosaprostol, a prostaglandin derivative used for the treatment of gastric and duodenal ulcers, using as key step the chemo- and stereoselective Michael addition of a Grignard reagent to an unprotected hydroxycyclopentenone. Georg Thieme Verlag Stuttgart.
An efficient asymmetric synthesis of prostaglandin E1
Rodriguez, Ana,Nomen, Miguel,Spur, Bernd Werner,Godfroid, Jean-Jacques
, p. 2655 - 2662 (2007/10/03)
An asymmetric total synthesis of Prostaglandin E1 (5) has been achieved in a two-component coupling process. The chiral hydroxycyclopentenone 6 was readily available from furan with 96% ee. The key reaction step was a kinetic enzymatic resolution followed by an in situ inversion. A catalytic asymmetric reduction of the γ-iodo vinyl ketone 19 with the Corey CBS catalyst gave the ω-side chain 7 with >96% ee. Conjugate addition using the reaction with dilithiocyanocuprate followed by mild cleavage of the silyl protective groups and enzymatic hydrolysis of the methyl ester 22 gave (-)-PGE1 5 in high yield.
