420837-90-7

Basic information

• Product Name: 2-Hexenoic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-3-methyl-6-phenyl-, 1,1-dimethylethyl ester, (2E,4S,5R)-
• CAS NO: 420837-90-7
• Molecular Formula: C22H33NO5
• Molecular Weight: 391.508
• Mol File: 420837-90-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Hexenoic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-3-methyl-6-phenyl-, 1,1-dimethylethyl ester, (2E,4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hexenoic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-3-methyl-6-phenyl-, 1,1-dimethylethyl ester, (2E,4S,5R)-(420837-90-7)
• EPA Substance Registry System: 2-Hexenoic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-3-methyl-6-phenyl-, 1,1-dimethylethyl ester, (2E,4S,5R)-(420837-90-7)

Safety Data

• Hazardous Substances Data: 420837-90-7(Hazardous Substances Data)

Upstream product

• 461696-75-3 tert-butyl (4S,5R,2E)-4-acetoxy-5-[N-(tert-butoxycarbonyl)amino]-3-methyl-6-phenylhex-2-enoate 
• 420837-88-3 tert-butyl (4R,5R,2E)-5-[N-(tert-butoxycarbonyl)amino]-4-hydroxy-3-methyl-6-phenylhex-2-enoate 
• 77119-85-8 N-(tert-butoxycarbonyl)-D-phenylalaninal 
• 420837-80-5 (3R,4R)-O-acetyl-4-[N-(tert-butoxycarbonyl)amino]-2-methyl-5-phenylpent-1-en-3-ol 
• 420837-78-1 (3R,4R)-4-[N-(tert-butoxycarbonyl)amino]-2-methyl-5-phenylpent-1-en-3-ol 
• 482374-27-6 (1-benzyl-2-hydroxy-3-methyl-but-3-enyl)-carbamic acid tert-butyl ester 
• 19901-50-9 methyl (2R)-2-(t-butoxycarbonylamino)-3-phenylpropionate 
• 106454-69-7 N-tert-butoxycarbonyl-D-Phenylalaninol 
• 461696-74-2 tert-butyl (4R,5R,2E)-4-acetoxy-5-[N-(tert-butoxycarbonyl)amino]-3-methyl-6-phenylhex-2-enoate 
• 420837-86-1 (3S,4R)-O-acetyl-4-[N-(tert-butoxycarbonyl)amino]-2-methyl-5-phenylpent-1-en-3-ol 
• 420837-83-8 (3S,4R)-4-[N-(tert-butoxycarbonyl)amino]-2-methyl-5-phenylpent-1-en-3-ol 

Downstream Products

• 420837-91-8 tert-butyl (4S,5R,2E)-5-[N-(tert-butyloxycarbonyl)amino]-3-methyl-4-methylsulfonyloxy-4-phenylhex-2-enoate 
• 420837-96-3 tert-butyl (2S,5R,3Z)-5-[N-(tert-butyloxycarbonyl)amino]-3-methyl-2-methylethyl-6-phenylhex-3-enoate 
• 420837-88-3 tert-butyl (4R,5R,2E)-5-[N-(tert-butoxycarbonyl)amino]-4-hydroxy-3-methyl-6-phenylhex-2-enoate 
• 420837-92-9 tert-butyl (2R,5R,3E)-5-[N-(tert-butyloxycarbonyl)amino]-3-methyl-2-methylethyl-6-phenylhex-3-enoate 
• 461696-74-2 tert-butyl (4R,5R,2E)-4-acetoxy-5-[N-(tert-butoxycarbonyl)amino]-3-methyl-6-phenylhex-2-enoate 
• 420837-89-4 tert-butyl (4R,5R,2E)-5-[N-(tert-butyloxycarbonyl)amino]-3-methyl-4-methylsulfonyloxy-6-phenylhex-2-enoate 
• 461696-75-3 tert-butyl (4S,5R,2E)-4-acetoxy-5-[N-(tert-butoxycarbonyl)amino]-3-methyl-6-phenylhex-2-enoate 

Relevant articles and documents

Diastereoselective Synthesis of ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-Type Dipeptide Isosteres by Organocopper-mediated anti-SN2′ Reaction

matrix presented Acyclic ψ[(E)-CH=CMe]- and ψ[(Z)-CH=CMe]-type dipeptide isosteres were efficiently synthesized. In a key reaction, α-alkylation of γ-mesyloxy-β-methyl-α,β-unsaturated esters with organocyanocuprates in diethyl ether or tetrahydrofuran preferentially afforded the ψ[(E)-CH=CMe]- or ψ[(Z)-CH=CMe]-isomer, respectively, via anti-SN2′ mechanism.