4214-78-2

Basic information

• Product Name: 5-Chloro-1-Methylpyridin-2-one
• Synonyms: 5-Chloro-1-Methylpyridin-2-one;5-chloro-1-Methylpyridin-2(1H)-one
• CAS NO: 4214-78-2
• Molecular Formula: C₆H₆ClNO
• Molecular Weight: 143.57094
• Mol File: 4214-78-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 241.8±33.0 °C(Predicted)
• Appearance: /
• Density: 1.29±0.1 g/cm3(Predicted)
• PKA: -0.41±0.62(Predicted)
• CAS DataBase Reference: 5-Chloro-1-Methylpyridin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-1-Methylpyridin-2-one(4214-78-2)
• EPA Substance Registry System: 5-Chloro-1-Methylpyridin-2-one(4214-78-2)

Safety Data

• Hazardous Substances Data: 4214-78-2(Hazardous Substances Data)

Usage

General Description

5-Chloro-1-Methylpyridin-2-one, also known as 5-chloro-2-pyridone, is a chemical compound with the molecular formula C6H5ClNO. It is a heterocyclic compound and a derivative of pyridine. This chemical is commonly used as an intermediate in the synthesis of pharmaceutical compounds. It also has potential applications in the production of pesticides, herbicides, and other agrochemicals. 5-Chloro-1-Methylpyridin-2-one is known for its ability to undergo various chemical reactions, making it a versatile building block for the synthesis of complex organic molecules. However, it is important to handle this chemical with care as it can be hazardous if not properly managed.

Upstream product

• 4214-79-3 5-chloro-2-pyridinol 
• 74-88-4 methyl iodide 
• 16110-09-1 2,5 dichloropyridine 
• 421-20-5 Methyl fluorosulfonate 
• 4214-79-3 5-chloro-1,2-dihydropyridin-2-one 

Downstream Products

• 16110-09-1 2,5 dichloropyridine 
• 112423-14-0 4-methoxy-1-methyl-3-phenylpyridin-2(1H)-one 

Relevant articles and documents

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Light-induced [2 + 2] cycloadditions for the construction of cyclobutane-fused pyridinyl sulfonyl fluorides

Cyclobutanes are an important class of motifs present in a wide range of natural products and other biologically significant molecules. A photocatalytic [2 + 2] cycloaddition between pyridones or isoquinolones and ethenesulfonyl fluoride was achieved, providing a portal to a class of unique cyclobutane-fused pyridinyl sulfonyl fluorides with quaternary rigid rings (30 examples). Further applications of these novel sulfonyl fluoride molecules in SuFEx click chemistry were also accomplished, providing the corresponding sulfonates and sulphonamides with reasonable yields.

Polyhalogenoaromatic Compounds. Part 42. 13C N.m.r. Spectra of Polyhalogeno-pyridines and pyrimidines

13C N.m.r. spectra are reported for a number of polyhaloheno-pyridines and -pyrimidines.Substituent effects have been calculated and the results used to assign structures.