421558-88-5Relevant articles and documents
First practical synthesis of enantiomerically pure (R)- and (S)-desmethylsibutramine (DMS) and unambiguous determination of their absolute configuration by single-crystal X-ray analysis
Han, Zhengxu,Krishnamurthy, Dhileepkumar,Pflum, Derek,Fang, Qun K.,Butler, Hal,Cameron,Wald, Stephen A.,Senanayake, Chris H.
, p. 107 - 109 (2002)
A practical synthesis of enantiomerically pure (R)-desmethylsibutramine [(R)-DMS] and (S)-desmethylsibutramine [(S)-DMS] is outlined along with an improved synthesis of racemic desmethylsibutramine. This route was used for kilo-scale production of enantio