421595-87-1

Basic information

• Product Name: Imidazo[1,2-a]pyridin-7-amine, N-(triphenylphosphoranylidene)-
• CAS NO: 421595-87-1
• Molecular Formula: C25H20N3P
• Molecular Weight: 393.428
• Mol File: 421595-87-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Imidazo[1,2-a]pyridin-7-amine, N-(triphenylphosphoranylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridin-7-amine, N-(triphenylphosphoranylidene)-(421595-87-1)
• EPA Substance Registry System: Imidazo[1,2-a]pyridin-7-amine, N-(triphenylphosphoranylidene)-(421595-87-1)

Safety Data

• Hazardous Substances Data: 421595-87-1(Hazardous Substances Data)

Upstream product

• 421596-48-7 ethyl N-(imidazo[1,2-a]pyridin-7-yl)carbamate 
• 421595-78-0 imidazo[1,2-a]pyridine-7-carbohydrazide 
• 421595-79-1 imidazo[1,2-a]pyridine-7-carbonyl azide 
• 421595-81-5 imidazo[1,2-a]pyridin-7-amine 
• 372147-49-4 imidazo[1,2-a]pyridine-7-carboxylic acid ethyl ester 
• 603-35-0 triphenylphosphine 
• 421595-83-7 7-azidoimidazo[1,2-a]pyridine 

Relevant articles and documents

Aminoimidazo[1,2-a]pyridines: Regioselective synthesis of substituted imidazonaphthyridines, azacarbolines and cyclazines

In order to study the regioselectivity of thermal cyclocondensation, aminoimidazo[1,2-a]pyridines (AIP) 5a-e were prepared, further converted into iminophosphoranes 7a-e, and ultimately converted regioselectively in angular annulated imidazonaphthyridines (IN) 8a, 10a, 11a, 12a or linear annulated dipyridoimidazole (DPI) 17a. From 2-substituted derivative 23, the peri annulated product 24a was obtained. The starting amines 5a-f reacted with aldehydes to yield regioselectively IN 8a-c, 10a-c, 11a-c, 12a,b, DPI 16a-e, 17a-d and TIBO like structures (±)-13 and 24a-c, as proved by X-ray analysis. The 1,2- or 1,4-addition between amines and α,β-unsaturated aldehydes concerning the pyridine and imidazole moieties is discussed in the light of these results.