423166-08-9

Basic information

• Product Name: N-(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)-1-(4-cyano-3-fluorobenzyl)-N-(2-oxoethyl)-1H-imidazole-5-carboxamide
• Synonyms: N-(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)-1-(4-cyano-3-fluorobenzyl)-N-(2-oxoethyl)-1H-imidazole-5-carboxamide
• CAS NO: 423166-08-9
• Molecular Weight: 665.239
• Mol File: 423166-08-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)-1-(4-cyano-3-fluorobenzyl)-N-(2-oxoethyl)-1H-imidazole-5-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)-1-(4-cyano-3-fluorobenzyl)-N-(2-oxoethyl)-1H-imidazole-5-carboxamide(423166-08-9)
• EPA Substance Registry System: N-(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)-1-(4-cyano-3-fluorobenzyl)-N-(2-oxoethyl)-1H-imidazole-5-carboxamide(423166-08-9)

Safety Data

• Hazardous Substances Data: 423166-08-9(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 59-50-7 4-Chloro-3-methylphenol 
• 423166-07-8 N-(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)-1-(4-cyano-3-fluorobenzyl)-N-(2-hydroxyethyl)-1H-imidazole-5-carboxamide 
• 423166-05-6 2-[(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)amino]ethanol 
• 350604-58-9 tetr-butyl(4-chloro-3-methylphenoxy)diphenylsilane 

Downstream Products

• 423166-09-0 4-[(5-{[(2R)-4-(5-{[tert-butyl(diphenyl)silyl]oxy}-2-chlorobenzyl)-2-methyl-3-oxopiperazin-1-yl]carbonyl}-1H-imidazol-1-yl)methyl]-2-fluorobenzonitrile 

Relevant articles and documents

Preparation of Substituted Piperazinones via Tandem Reductive Amination-(N,N′-Acyl Transfer)-Cyclization

matrix presented A one-pot, tandem reductive amination-transamidation-cyclization reaction was employed to produce substituted piperazin-2-ones in good yields. Various amino acid methyl esters and transferable acyl groups were examined to establish the re