42436-56-6

Basic information

• Product Name: 1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine
• Synonyms: 1,2-Dilauroyl-sn-glycero-3-phosphorylethanolamine (DLPE)
• CAS NO: 42436-56-6
• Molecular Formula: C₂₉H₅₈NO₈P
• Molecular Weight: 579.746481
• Mol File: 42436-56-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine(42436-56-6)
• EPA Substance Registry System: 1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine(42436-56-6)

Safety Data

• Hazardous Substances Data: 42436-56-6(Hazardous Substances Data)

Usage

General Description

1,2-Dilauroyl-sn-Glycero-3-PhosphatidylethanolaMine (DLPE) is a synthetic phospholipid derivative that belongs to the family of phosphatidylethanolamines. It is composed of two lauric acid chains attached to a glycerol backbone, with an ethanolamine head group. DLPE is often used in biomedical research as a model membrane lipid due to its structural similarity to natural phospholipids found in cell membranes. It is also utilized in the development of liposomal drug delivery systems and as a component in lipid bilayer systems for studying membrane protein function. Additionally, DLPE has been investigated for its potential role in cell signaling, membrane fusion, and other biological processes.

Upstream product

• 17598-94-6 dodecanoic acid 1,1'-[(1S)-1-(hydroxymethyl)-1,2-ethanediyl]ester 

Relevant articles and documents

A diacyl phosphatidyl ethanolamine preparation method (by machine translation)

The invention provides a diacyl phosphatidyl ethanolamine preparation method, comprises the following steps: (1) solvent and organic/inorganic alkali under the action of, the formula I compound and phosphorus reagent undergo the substitution reaction, formula a intermediate 1; (2) in the same reaction system, intermediate 1 of an organic/inorganic the presence of an alkali, with 2 - (N - [...] carbonyl amino) ethanol or N - Boc protection of the ethanolamine undergo the substitution reaction, formula b intermediate 2; (3) in the same reaction system, intermediate 2 under the action of the oxidizing agent in the oxidation reaction, the compound of formula II; (4) the formula II compound in the solvent, under the action of alkali, phospholipid base hydrolysis, formula III compound. The advantage of this invention is characterized in that: the invention only needs two-step synthesis of the target product can be obtained, and the method is easy to control conditions, after treatment is simple, less side reaction, high yield, consistent with the requirements of industrial production. (by machine translation)