4264-29-3 Usage
Description
(E)-2-Nitrostilbene, also known as 1-nitro-2-(E-phenylethenyl) benzene, is a chemical compound with the molecular formula C14H11NO2. It is a yellow crystalline solid that possesses distinctive chemical and physical properties due to the presence of a nitro group (-NO2). (E)-2-Nitrostilbene is recognized for its potential applications in various fields, including pharmaceuticals, dyes, and perfumes, as well as its use as a key intermediate in organic synthesis. Furthermore, (E)-2-Nitrostilbene has garnered interest for its potential antimicrobial and antitumor properties, which makes it a promising candidate for further pharmacological research.
Uses
Used in Pharmaceutical Industry:
(E)-2-Nitrostilbene is used as a key intermediate for the production of various pharmaceuticals. Its unique chemical structure allows it to be a valuable component in the synthesis of different medicinal compounds, contributing to the development of novel drugs and therapies.
Used in Dye Industry:
In the dye industry, (E)-2-Nitrostilbene is utilized as a starting material for the synthesis of various dyes. Its yellow crystalline nature and chemical properties make it suitable for creating a range of colorants used in different applications, such as textiles, plastics, and printing inks.
Used in Perfume Industry:
(E)-2-Nitrostilbene is also used as a component in the perfume industry, where its distinctive chemical properties contribute to the creation of unique and complex fragrances. Its ability to be a part of organic synthesis allows for the development of novel scent compounds that can be used in various perfume formulations.
Used in Organic Synthesis:
(E)-2-Nitrostilbene serves as a crucial intermediate in organic synthesis, enabling the preparation of a wide array of organic compounds. Its reactivity and potential applications make it a valuable chemical in both industrial and academic settings, facilitating the development of new materials and compounds with diverse uses.
Used in Antimicrobial Applications:
(E)-2-Nitrostilbene has been studied for its potential antimicrobial properties, making it an interesting target for further research in the development of new antimicrobial agents. Its ability to inhibit the growth of certain microorganisms could lead to the creation of novel treatments and preventive measures against various infections.
Used in Antitumor Research:
The antitumor potential of (E)-2-Nitrostilbene has also been a subject of interest, with its possible application in the development of new cancer therapies. Further pharmacological research could reveal its effectiveness in targeting specific cancer cells and contribute to the advancement of cancer treatment options.
Check Digit Verification of cas no
The CAS Registry Mumber 4264-29-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,6 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4264-29:
(6*4)+(5*2)+(4*6)+(3*4)+(2*2)+(1*9)=83
83 % 10 = 3
So 4264-29-3 is a valid CAS Registry Number.
4264-29-3Relevant articles and documents
Wittig Olefination Using Phosphonium Ion-Pair Reagents Incorporating an Endogenous Base
Vetter, Anna C.,Gilheany, Declan G.,Nikitin, Kirill
, p. 1457 - 1462 (2021/03/08)
Despite common perception, the use of strong bases in Wittig chemistry is utterly unnecessary: we report a series of novel ion-pair phosphonium carboxylate reagents which are essentially "storable ylides". These reagents are straightforwardly prepared in excellent yields, and their fluxional nature permits clean olefination of a broad range of aldehydes and even hemiacetals.
Counterion Control of t-BuO-Mediated Single Electron Transfer to Nitrostilbenes to Construct N-Hydroxyindoles or Oxindoles
Driver, Tom G.,Sung, Siyoung,Wink, Donald J.,Zadrozny, Joseph M.,Zhao, Yingwei,Zhu, Haoran
supporting information, p. 19207 - 19213 (2021/08/09)
tert-Butoxide unlocks new reactivity patterns embedded in nitroarenes. Exposure of nitrostilbenes to sodium tert-butoxide was found to produce N-hydroxyindoles at room temperature without an additive. Changing the counterion to potassium changed the reaction outcome to yield solely oxindoles through an unprecedented dioxygen-transfer reaction followed by a 1,2-phenyl migration. Mechanistic experiments established that these reactions proceed via radical intermediates and suggest that counterion coordination controls whether an oxindole or N-hydroxyindole product is formed.
Palladium-Based Catalysts Supported by Unsymmetrical XYC–1 Type Pincer Ligands: C5 Arylation of Imidazoles and Synthesis of Octinoxate Utilizing the Mizoroki–Heck Reaction
Maji, Ankur,Singh, Ovender,Singh, Sain,Mohanty, Aurobinda,Maji, Pradip K.,Ghosh, Kaushik
, p. 1596 - 1611 (2020/04/29)
A series of new unsymmetrical (XYC–1 type) palladacycles (C1–C4) were designed and synthesized with simple anchoring ligands L1–4H (L1H = 2-((2-(4-methoxybenzylidene)-1-phenylhydrazinyl)methyl)pyridine, L2H = N,N-dimethyl-4-((2-phenyl-2-(pyridin-2-ylmethyl)hydrazono)methyl)aniline, L3H = N,N-diethyl-4-((2-phenyl-2-(pyridin-2-ylmethyl)hydrazono)methyl) aniline and L4H = 4-(4-((2-phenyl-2-(pyridin-2-ylmethyl)hydrazono) methyl)phenyl)morpholine H = dissociable proton). Molecular structure of catalysts (C1–C4) were further established by single X-ray crystallographic studies. The catalytic performance of palladacycles (C1–C4) was explored with the direct Csp2–H arylation of imidazoles with aryl halide derivatives. These palladacycles were also applied for investigating of Mizoroki–Heck reactions with aryl halides and acrylate derivatives. During catalytic cycle in situ generated Pd(0) nanoparticles were characterized by XPS, SEM and TEM analysis and possible reaction pathways were proposed. The catalyst was employed as a pre-catalyst for the gram-scale synthesis of octinoxate, which is utilized as a UV-B sunscreen agent.
