58810-39-2

Basic information

• Product Name: 1H-Indole, 1-(benzoyloxy)-2-phenyl-
• CAS NO: 58810-39-2
• Molecular Formula: C21H15NO2
• Molecular Weight: 313.356
• Mol File: 58810-39-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 1-(benzoyloxy)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 1-(benzoyloxy)-2-phenyl-(58810-39-2)
• EPA Substance Registry System: 1H-Indole, 1-(benzoyloxy)-2-phenyl-(58810-39-2)

Safety Data

• Hazardous Substances Data: 58810-39-2(Hazardous Substances Data)

Usage

Structure

Bicyclic, with a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring

Substituents

A benzoyloxy group attached to position 1 of the indole ring and a phenyl group attached to position 2

Uses

Organic synthesis and pharmaceutical research, key intermediate in the production of various pharmaceuticals and agrochemicals

Importance

Valuable building block for the synthesis of complex organic compounds due to its structural properties and reactivity.

Upstream product

• 1613-37-2 Quinoline N-oxide 
• 1859-39-8 2-phenyl-N-hydroxyindole 
• 98-88-4 benzoyl chloride 
• 100-42-5 styrene 
• 577-19-5 2-nitrophenyl bromide 
• 4264-29-3 (E)-2-nitrostilbene 

Downstream Products

• 64968-18-9 1-benzoyloxy-2-phenyl-3-(2-quinolyl)indole 
• 57152-69-9 2-phenyl-1H-indol-3-yl benzoate 
• 64968-19-0 1-hydroxy-2-phenyl-3-(2-quinolyl)indole 

Relevant articles and documents

Counterion Control of t-BuO-Mediated Single Electron Transfer to Nitrostilbenes to Construct N-Hydroxyindoles or Oxindoles

tert-Butoxide unlocks new reactivity patterns embedded in nitroarenes. Exposure of nitrostilbenes to sodium tert-butoxide was found to produce N-hydroxyindoles at room temperature without an additive. Changing the counterion to potassium changed the reaction outcome to yield solely oxindoles through an unprecedented dioxygen-transfer reaction followed by a 1,2-phenyl migration. Mechanistic experiments established that these reactions proceed via radical intermediates and suggest that counterion coordination controls whether an oxindole or N-hydroxyindole product is formed.

Studies on tertiary amine oxides. LXXI. Some electrophilic reactions of 1-hydroxy-2-phenylindole

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