42916-73-4

Basic information

• Product Name: 1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE
• Synonyms: 1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE;p-Valeroylbiphenyl;1-[1,1'-biphenyl]-4-yl-1-pentanon;1-(4-phenylphenyl)pentan-1-one;4PhenylValerophenone,4ValerylBiphenyl;4-Valerylbiphenyl;4-Pentanoylbiphenyl;1-[1,1'-BIPHENYL]-4-
• CAS NO: 42916-73-4
• Molecular Formula: C₁₇H₁₈O
• Molecular Weight: 238.32
• Mol File: 42916-73-4.mol
• Article Data: 16

Chemical Properties

• Melting Point: 76-78 °C
• Boiling Point: 368.7 °C at 760 mmHg
• Flash Point: 158.8 °C
• Appearance: /
• Density: 1.01 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE(42916-73-4)
• EPA Substance Registry System: 1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE(42916-73-4)

Safety Data

• Hazardous Substances Data: 42916-73-4(Hazardous Substances Data)

Usage

General Description

1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE is a chemical compound with the molecular formula C19H18O. It is an aromatic ketone that consists of a pentanone group attached to a biphenyl ring. 1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE is often used in organic synthesis as a building block for more complex organic molecules. It is also used in the production of pharmaceuticals and agrochemicals. Additionally, 1-[1,1'-BIPHENYL]-4-YL-1-PENTANONE is used as a fragrance ingredient in perfumes and cosmetics. Due to its versatile applications, this chemical compound is of significant interest to researchers and industries in the fields of chemistry, pharmaceuticals, and fragrance production.

Upstream product

• 7295-44-5 4'-bromovalerophenone 
• 71478-47-2 phenylmanganese(II) chloride 
• 7116-96-3 1-pentyl-4-phenylbenzene 
• 109-72-8 n-butyllithium 
• 591-51-5 phenyllithium 
• 192436-83-2 4-bromo-N-methoxy-N-methylbenzamide 
• 92867-95-3 [1,1'-biphenyl]-4-yl(1H-imidazol-1-yl)methanone 
• 92-52-4 biphenyl 
• 2082-59-9 pentanoic anhydride 
• 3218-36-8 4-Phenylbenzaldehyde 
• 120-92-3 cyclopentanone 
• 98-80-6 phenylboronic acid 
• 100-59-4 phenylmagnesium chloride 
• 50673-89-7 1-([1,1'-biphenyl]-4-yl)pentan-1-ol 

Downstream Products

• 169601-42-7 6-[1,1'-biphenyl]-4-yl-6-butyl-5,6-dihydro-4-hydroxy-2H-pyran-2-one 
• 69971-79-5 4-iodoo-4'-n-pentylbiphenyl 
• 56741-21-0 4'-pentyl-1,1'-biphenyl-4-carbaldehyde 
• 40817-08-1 4-cyano-4'-pentyl-1,1'-biphenyl 
• 7116-96-3 1-pentyl-4-phenylbenzene 

Relevant articles and documents

Light-DrivenN-Heterocyclic Carbene Catalysis Using Alkylborates

Radical-radical coupling, the selective reaction between two different radical species, has contributed to the methodology for connecting bulky units. Light-drivenN-heterocyclic carbene (NHC) organocatalysis is recognized as a state-of-the-art methodology enabling radical-radical coupling. The catalytic process involves forming an acyl azolium intermediate from the NHC catalyst and an acyl donor, followed by single electron reduction of this key intermediate, which is largely dependent on the photoredox catalyst. We designed a radical NHC catalysis in which the direct photoexcitation of a borate to form a high reducing agent facilitated the single electron reduction event. The borate produces an alkyl radical for the single electron transfer process to accomplish the radical-radical coupling. This protocol enables cross-coupling between alkylborates and acyl imidazoles in addition to radical relay-type alkylacylations of alkenes with alkylborates and acyl imidazoles, affording ketones with a broad scope.

Scalable Aerobic Oxidation of Alcohols Using Catalytic DDQ/HNO3

A selective, practical, and scalable aerobic oxidation of alcohols is described that uses catalytic amounts of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and HNO3, with molecular oxygen serving as the terminal oxidant. The method was successfully applied to the oxidation of a wide range of benzylic, propargylic, and allylic alcohols, including two natural products, namely, carveol and podophyllotoxin. The conditions are also applicable to the selective oxidative deprotection of p-methoxybenzyl ethers.

Suzuki-Miyaura coupling of simple ketones via activation of unstrained carbon-carbon bonds

Here, we describe that simple ketones can be efficiently employed as electrophiles in Suzuki-Miyaura coupling reactions via catalytic activation of unstrained C-C bonds. A range of common ketones, such as cyclopentanones, acetophenones, acetone and 1-indanones, could be directly coupled with various arylboronates in high site-selectivity, which offers a distinct entry to more functionalized aromatic ketones. Preliminary mechanistic study suggests that the ketone α-C-C bond was cleaved via oxidative addition.