42974-18-5

Basic information

• Product Name: 3,4-Dibromocoumarin
• Synonyms: 3,4-Dibromocoumarin;3,4-DibroMo-chroMan-2-one;2H-1-Benzopyran-2-one, 3,4-dibroMo-3,4-dihydro-
• CAS NO: 42974-18-5
• Molecular Formula: C₉H₆Br₂O₂
• Molecular Weight: 303.93486
• Mol File: 42974-18-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-Dibromocoumarin(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dibromocoumarin(42974-18-5)
• EPA Substance Registry System: 3,4-Dibromocoumarin(42974-18-5)

Safety Data

• Hazardous Substances Data: 42974-18-5(Hazardous Substances Data)

Upstream product

• 91-64-5 coumarin 

Downstream Products

• 55982-08-6 (hydroxy-2 phenyl)-6 phenyl-2 oxo-4 dihydro-3,4 pyrimidine 
• 91-64-5 coumarin 
• 939-18-4 3-bromo-2H-chromen-2-one 
• 10035-10-6 hydrogen bromide 
• 19063-55-9 6-bromo-2H-chromen-2-one 
• 58309-97-0 3,6-dibromo-2H-chromen-2-one 
• 55982-09-7 (hydroxy-2 phenyl)-6 methyl-2 oxo-4 dihydro-3,4 pyrimidine 
• 938-40-9 4-Bromo-2H-1-benzopyran-2-one 
• 496-41-3 Benzofuran-2-carboxylic acid 
• 1092776-44-7 3-bromo-1,2-dimethylindazolium bromide 

Relevant articles and documents

Synthesis of 3-(5-methylthiophen-2-yl)coumarins and their photochromic dihetarylethene derivatives

Novel unsymmetrical di(thienyl)maleic acid anhydride, including coumarin moiety, has been designed and synthesized. Its photochromism study and fatigue resistance estimation are reported. Microwave-assisted procedure has been successfully used for synthesis of 3-(5-methylthiophen-2-yl)coumarins.

Design, synthesis and in vitro antibacterial/antifungal evaluation of novel 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid derivatives

A series of 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)quinoline-3-carboxylic acid (norfloxacin) derivatives were prepared according to the principle of combinating bioactive substructures and tested for their activities against five plant pathogenic bacteria and three fungi in vitro. The preliminary bioassays indicated that almost all synthesized target compounds retained the antibacterial activities of norfloxacin and had some antifungal activities as carboxylic acid amide compounds. The activities of compounds 1 and 22 against Xanthomonas oryzae were better than norfloxacin and all tested compounds had better antibacterial activities as compared to the agricultural streptomycin sulfate (a commercial bactericide) against X. oryzae, Xanthomonas axonopodis and Erwinia aroideae. Additionally, compounds 2 and 20 displayed good antifungal activities against Rhizoctonia solani and their inhibition of growth reached 83% and 94% respectively at the concentration of 200 mg/L.

A convenient halogenation of α,β-unsaturated carbonyl compounds with OXONE and hydrohalic acid (HBr,HCl)

Mixtures of OXONE and hydrobromic acid or hydrochloric acid afford solutions of bromine or chlorine, respectively, α-Bromo- or α-chloro-α,β-unsaturated carbonyl compounds were prepared by addition of hydrobromic acid or hydrochloric acid to the mixture of