939-18-4

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 3-bromo-
• Synonyms: 2H-1-Benzopyran-2-one, 3-bromo-;3-BROMO-2-CHROMENONE;3-Bromo-chromen-2-one;3-Bromo-2H-chromen-2-one
• CAS NO: 939-18-4
• Molecular Formula: C₉H₅BrO₂
• Molecular Weight: 225.0388
• Mol File: 939-18-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 250 °C
• Boiling Point: 344.3±30.0 °C(Predicted)
• Appearance: /
• Density: 1.738±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 3-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 3-bromo-(939-18-4)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 3-bromo-(939-18-4)

Safety Data

• Hazardous Substances Data: 939-18-4(Hazardous Substances Data)

Usage

Description

2H-1-Benzopyran-2-one, 3-bromo-, also known as 3-Bromo-2H-chromen-2-one, is a chemical compound that is a derivative of Coumarin (C755380). It possesses unique chemical properties and is recognized for its potential applications in various fields.
Used in Antiviral Applications:
3-Bromo-2H-chromen-2-one is used as a sensitizer for the inactivation of viruses. It enhances the effectiveness of processes aimed at neutralizing or disabling viruses, thereby contributing to the development of antiviral strategies and products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Bromo-2H-chromen-2-one is utilized as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a building block for the development of new drugs with potential therapeutic applications.
Used in Chemical Research:
3-Bromo-2H-chromen-2-one is also used in chemical research as a model compound to study the properties and reactions of coumarin derivatives. This helps researchers to better understand the behavior of similar compounds and to develop new methods for their synthesis and application.

Upstream product

• 42974-18-5 3,4-dibromo-3,4-dihydrocoumarin 

Downstream Products

• 72167-83-0 4-(p-tolylthio)-2H-chromen-2-one 
• 27183-56-8 4-((4-chlorophenyl)thio)-2H-chromen-2-one 
• 27129-32-4 4-phenylsulphenyl-2H-chromene-2-one 
• 449179-59-3 3-(4-tert-butylphenoxy)chromen-2-one 
• 449179-60-6 3-(4-fluorophenoxy)chromen-2-one 
• 10465-91-5 3-(4-chlorophenyl)-2H-chromen-2-one 
• 1416620-49-9 C₁₇H₁₇N₃O₂ 
• 1416620-48-8 C₁₈H₁₂N₄O₄ 

Relevant articles and documents

Dimethyl sulfoxide mediated elimination reactions in 3-aryl 2,3-dihalopropanoates: Scope and mechanistic insights

(Chemical Equation Presented) Dimethyl sulfoxide (DMSO) efficiently causes the reductive elimination of 3-aryl 2,3-dibromopropanoates to cinnamates with good yield. With 3-phenyl 2,3-dihalopropanoates, debromination is the major pathway providing 3-phenylacrylate derivatives in high yields, whereas dehydrobromination is a competing pathway with thiophene derivatives. 1H NMR, 81Br NMR, and MS techniques indicated the formation of brominated-DMSO, MeBr, and HBr as byproducts in this transformation with no evidence for the formation of Br2. The dual role of DMSO as a nucleophile and bromine scavenger accounts for the products formed in this reaction.