430534-91-1

Basic information

• Product Name: 4-chloro-3-fluorobenzoylchloride oxime
• Synonyms: 4-chloro-3-fluorobenzoylchloride oxime
• CAS NO: 430534-91-1
• Molecular Weight: 208.019
• Mol File: 430534-91-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 4-chloro-3-fluorobenzoylchloride oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-3-fluorobenzoylchloride oxime(430534-91-1)
• EPA Substance Registry System: 4-chloro-3-fluorobenzoylchloride oxime(430534-91-1)

Safety Data

• Hazardous Substances Data: 430534-91-1(Hazardous Substances Data)

Upstream product

• 202925-09-5 4-chloro-3-fluorobenzaldehyde oxime 
• 5527-95-7 4-chloro-3-fluorobenzaldehyde 

Downstream Products

• 677729-04-3 C₁₀H₉ClFNO₂ 
• 1239576-12-5 4-chloro-3-(4-chloro-3-fluorophenyl)-N-((1R,3S)-3-hydroxycyclohexyl)isoxazole-5-carboxamide 
• 1239576-24-9 4-chloro-3-(4-chloro-3-fluorophenyl)isoxazole-5-carboxylic acid 
• 1325228-74-7 C₁₀H₆Cl₂FNO₂ 
• 1325228-72-5 C₁₂H₈Cl₂FNO₃ 
• 1126636-64-3 C₁₀H₇ClFNO₂ 

Relevant articles and documents

Triazole alcohol derivative as well as preparation method and application thereof

The invention relates to a triazole alcohol derivative as well as a preparation method and application thereof. The chemical structure of the triazole alcohol derivative is shown as a formula I, R1 represents a benzene ring or a substituted benzene ring, and substituent groups of the substituted benzene ring can be located at all positions of the benzene ring, can be mono-substituted or multi-substituted, and can be selected from a) halogen which is F and Cl; b) an electron withdrawing group which is cyano or trifluoromethyl; c ) a lower alkyl of 1-4 carbon atoms or a halogen substituted loweralkyl; and d) lower alkoxy of 1-4 carbon atoms or halogen substituted lower alkoxy. The compound of the invention has strong antifungal activity, has the advantages of low toxicity, wide antibacterial spectrum and the like, and can be used for preparing antifungal drugs.

Discovery of Natural Product-Based Fungicides (II): Semisynthesis and Biological Activity of Sarisan Attached 3-Phenylisoxazolines as Antifungal Agents

Many phytopathogenic fungi cause severe damage to crop yields. In continuation of our research aimed at the discovery and development of natural products-based fungicides, a series of thirty-one sarisan attached 3-phenylisoxazolines were synthesized and evaluated for their antifungal activities against five phytopathogenic fungi (B. cinerea, C. lagenarium, A. solani, F. solani, and F. graminearum). Among all title sarisan derivatives, compounds IV2, IV14 and IV23 showed potent antifungal activity against some phytopathogenic fungi. In particular, compound IV2 exhibited a broad-spectrum and more potent antifungal activity against A. solani, F. solani, and F. graminearum than the commercial fungicide Hymexazol. In addition, compounds IV2, IV14 and IV23 also displayed relative low toxicity on normal NRK-52E cells. This work will give some insights into the development of sarisan derivatives as new fungicide candidates in plant protection.

Triazole alcohol derivative and preparation method and application thereof

The invention relates to a triazole alcohol derivative and a preparation method and application thereof. The chemical structure of the triazole alcohol derivative is as shown in the formula I. The invention also provides salt of the compound, a pharmaceutical composition, a preparation method and application. The compound of the invention has strong antifungal activity, has advantages of low toxicity and wide antimicrobial spectrum, and can be used for preparation of antifungal drugs.