43153-04-4

Basic information

• Product Name: 4-ForMyl-α-Methyl-benzeneacetic Acid Ethyl Ester
• Synonyms: 4-ForMyl-α-Methyl-benzeneacetic Acid Ethyl Ester;rac 2-(4-ForMylphenyl)propionic Acid Ethyl Ester;Ibuprofen Impurity 25;2-(4-Formylphenyl)propionic Acid Ethyl Ester
• CAS NO: 43153-04-4
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.23776
• Product Categories: Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 43153-04-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 155 °C(Press: 0.4 Torr)
• Appearance: /
• Density: 1.098±0.06 g/cm3(Predicted)
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: 4-ForMyl-α-Methyl-benzeneacetic Acid Ethyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ForMyl-α-Methyl-benzeneacetic Acid Ethyl Ester(43153-04-4)
• EPA Substance Registry System: 4-ForMyl-α-Methyl-benzeneacetic Acid Ethyl Ester(43153-04-4)

Safety Data

• Hazardous Substances Data: 43153-04-4(Hazardous Substances Data)

Usage

Uses

Ibuprofen Impurity K (F700900) derivative.

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 2510-99-8 ethyl 2-phenylpropanoate 
• 492-37-5 hydratropic acid 
• 32868-25-0 2-(4-amminofenil)propionico d'etile 
• 100-52-7 benzaldehyde 
• 105-37-3 Ethyl propionate 
• 118618-32-9 ethyl 2-(p-cyano-phenyl)-propionate 
• 43153-03-3 2-(4-chloromethylphenyl)-propionic ethyl ester 
• 41283-72-1 ibuprofen ethyl ester 

Downstream Products

• 118618-33-0 ethyl 2--propionate 
• 69956-74-7 ethyl 2-[4-(2-oxo-1-cyclohexylidenemethyl)phenyl]propionate 
• 69956-75-8 ethyl 2-[4-(2-oxo-1-cyclopentylidenemethyl)phenyl]propionate 
• 111128-12-2 2-[4-(bromomethyl)phenyl]propanoic acid 
• 1012312-21-8 ethyl 2-[4-(thiolan-2-ylidenemethyl)phenyl]propionate 
• 1012312-23-0 ethyl 2-{4-[(1,1-dioxotetrahydro-1λ6-thiophen-2-yl)hydroxymethyl]phenyl}propionate 
• 1012312-17-2 Ethyl 2-{4-[hydroxy(2-oxothiolan-3-yl)methyl]phenyl}propionate 
• 69956-78-1 2-[4-(2-Oxo-1-cycloheptylidenemethyl)phenyl]propionic acid 
• 50685-17-1 2-(4-benzothiazol-2-yl-phenyl)-propionic acid 
• 52787-34-5 2-[4-(4-oxo-thiazolidin-2-yl)-phenyl]-propionic acid 
• 43153-03-3 2-(4-chloromethylphenyl)-propionic ethyl ester 
• 69956-78-1 2-{4-[2-Oxo-cyclohept-(E)-ylidenemethyl]-phenyl}-propionic acid 
• 69956-77-0 2-[4-(2-oxo-1-cyclohexyliden methyl)-phenyl]propionic acid 
• 43153-07-7 2-(4-formylphenyl)propanoic acid 

Relevant articles and documents

Method for synthesizing P-bromomethyl isobenzopropionic acid

The invention provides a method for synthesizing p-bromomethyl isobenzopropionic acid, and relates to the technical field of organic synthesis. The synthesis method disclosed by the invention comprises the synthesis of isobenzoates. Vilsmeier Reagent preparation method comprises the following steps: synthesizing aldehyde isopropylparaben, synthesizing methyl isopropylbenzene, separating and purifying bromomethyl isobenzopropionic acid and, and the like. The final para-position selectivity of the method can reach 90 - 97%, and the three-waste yield is greatly reduced.

Conjugate addition of lithium enolates to aromatic carbonyl compounds complexed with aluminum tris(2, 6-diphenylphenoxide) (ATPH)

Various lithium enolates of esters undergo effective 1, 6-addition to aromatic carbonyl compounds in the presence of aluminum tris(2, 6-diphenylphenoxide)(ATPH). Thieme.

Antiinflammatory derivatives of phenylacetic acid; derivatives substituted by a heterocycle at the phenyl ring

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