43193-60-8

Basic information

• Product Name: pyrazinetetracarboxylic acid
• Synonyms: pyrazinetetracarboxylic acid;2,3,5,6-Pyrazinetetracarboxylic acid;Pyrazine-2,3,5,6-tetracarboxylic acid;pyrazinetetracarboxylic acid（WS204348）
• CAS NO: 43193-60-8
• Molecular Formula: C₈H₄N₂O₈
• Molecular Weight: 258.14184
• EINECS: 256-137-3
• Mol File: 43193-60-8.mol
• Article Data: 9

Chemical Properties

• Melting Point: 205℃ (decomposition)
• Boiling Point: 660°Cat760mmHg
• Flash Point: 353°C
• Appearance: /
• Density: 2.032g/cm³
• Vapor Pressure: 2.54E-18mmHg at 25°C
• Refractive Index: 1.727
• PKA: 0.58±0.10(Predicted)
• CAS DataBase Reference: pyrazinetetracarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: pyrazinetetracarboxylic acid(43193-60-8)
• EPA Substance Registry System: pyrazinetetracarboxylic acid(43193-60-8)

Safety Data

• Hazardous Substances Data: 43193-60-8(Hazardous Substances Data)

Usage

Description

Pyrazinetetracarboxylic acid, also known as PTCA, is an organic compound with the molecular formula C8H4N2O8. It is a derivative of pyrazine, featuring a pyrazine ring with four carboxylic acid groups attached to it. PTCA is recognized for its unique structural and coordination properties, which make it a versatile compound in various applications.

Uses

Used in Chemical Synthesis:
Pyrazinetetracarboxylic acid is used as a complexing agent in the synthesis of coordination compounds and metal-organic frameworks. Its ability to form complexes with metal ions is crucial for creating new materials with specific properties.
Used in Pharmaceutical Development:
PTCA is being studied for its potential use in pharmaceuticals, where its unique structure could contribute to the development of new drugs. The exploration of its properties is ongoing to understand its full potential in this field.
Used in Electronics and Materials Science:
Due to its coordination properties, Pyrazinetetracarboxylic acid is also considered for use in electronic and materials applications. Its capacity to interact with other molecules and ions could lead to advancements in material science for various technologies.
Used in Antiviral and Antimicrobial Research:
Pyrazinetetracarboxylic acid has been investigated for its potential as an antiviral and antimicrobial agent. The research in this area is still in the early stages, and further studies are required to fully explore and understand its effectiveness and possible applications in these fields.

InChI:InChI=1/C8H4N2O8/c11-5(12)1-2(6(13)14)10-4(8(17)18)3(9-1)7(15)16/h(H,11,12)(H,13,14)(H,15,16)(H,17,18)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 92-82-0 Phenazin 
• 1124-11-4 Tetramethylpyrazine 
• 6924-99-8 Quinoxaline-2,3-dicarboxylic acid 
• 4569-77-1 2-amino-3-hydroxy-phenazine 
• 655-86-7 2,3-diaminephenazine 

Downstream Products

• 35042-21-8 tetramethyl pyrazine-2,3,5,6-tetracarboxylate 
• 290-37-9 1,4-pyrazine 
• 103150-78-3 diethyl pyrazine-2,5-dicarboxylate 

Relevant articles and documents

Self-assembly of alternating left- and right-handed infinite Cd(II) helicates into a 2D open framework structure

Pyrazine-2,3,5,6-tetracarboxylic acid (ptcH4) reacts with Cd(NO3)2·6H2O at room temperature in the presence of pyridine to form a 2D open framework built from alternating left- and right-handed helicates with the empirical formula, {[Cd2(ptc)·(py)5·H2O]·5H2O·py}n, 1. Lattice water and pyridine molecules form an intricate array of H-bonding with the 2D sheets leading to a 3D structure. This compound crystallizes in the monoclinic space group C2/c with the following lattice parameters-a=24.103(2), b=13.480(5), c=29.176(4) A?, β=109.427(3)°, V=8940(4) A?3, Z=8, R1=0.0513, wR2=0.1552, S=1.085.

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Facile construction of two-dimensional coordination polymers with a well-designed redox-active organic linker for improved lithium ion battery performance

A well-designed redox-active organic linker, pyrazine-2,3,5,6-tetracarboxylate (H4pztc) with brimming active sites for lithium ions storage was utilized to construct coordination polymers (CPs) via a facile hydrothermal reaction. Those two isostructural two-dimensional (2D) CPs, namely [M2(pztc)(H2O)6]n (M=Co for 1 and Ni for 2), delivered excellent reversible capacities and stable cycling performance as anodes in lithium ion batteries. As demonstrated in electrochemical studies, 1 and 2 can achieve highly reversible capacities of 815 and 536 mA h g?1 at 200 mA g?1 for 150 cycles, respectively, best performed for the reported 2D-CP-based anode materials. The electrochemical mechanism studies showed that the remarkable performances can be ascribed to the synergistic Li-storage redox reactions of metal centers and organic moieties. Our work highlights the opportunities of using a well-designed organic ligand to construct low-dimensional CPs as new type of electrode materials for advanced lithium ion batteries.

1D slide-fastener-like coordination polymers of Mn(II) derived from pyrazine-2,3,5,6-tetracarboxylic acid

Two new 1D slide-fastener-like coordination polymers {[Mn2(pztc)(phen)2(H2O)2]·4H2O}n (1) and {[Mn2(pztc)(bpy)2(H2O)2]·2H2O}n (2) have been synthesized by the reactions of pyrazine-2,3,5,6-tetracarboxylic acid (pztcH4) and Mn(OAc)2·4H2O in the presence of 1,10-phenanthroline (phen) or 2,2′-bipyridine (bpy) under hydrothermal conditions and characterized by elemental analyses, FT-IR, TGA and X-ray diffraction. In complex 1 and 2, metal ions are bridged by pyrazine-2,3,5,6-tetracarboxylate, coordinating in a hexadentate manner, so forming 1D polymeric chains. The remaining coordination sites of the metal ions are occupied by one O atom of water molecule and two N atoms of the terminal ligand (phen or bpy). IR spectra and thermal analysis data are in agreement with the crystal structure.