43217-89-6

Basic information

• Product Name: cholesta-5,7-diene-1 alpha,3 beta-diol
• Synonyms: cholesta-5,7-diene-1 alpha,3 beta-diol
• CAS NO: 43217-89-6
• Molecular Formula: C₂₇H₄₄O₂
• Molecular Weight: 400.64
• Mol File: 43217-89-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 528°C at 760 mmHg
• Flash Point: 222.3°C
• Appearance: /
• Density: 1.04g/cm³
• Vapor Pressure: 2.37E-13mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: cholesta-5,7-diene-1 alpha,3 beta-diol(CAS DataBase Reference)
• NIST Chemistry Reference: cholesta-5,7-diene-1 alpha,3 beta-diol(43217-89-6)
• EPA Substance Registry System: cholesta-5,7-diene-1 alpha,3 beta-diol(43217-89-6)

Safety Data

• Hazardous Substances Data: 43217-89-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C27H44O2/c1-17(2)7-6-8-18(3)22-11-12-23-21-10-9-19-15-20(28)16-25(29)27(19,5)24(21)13-14-26(22,23)4/h9-10,17-18,20,22-25,28-29H,6-8,11-16H2,1-5H3/t18-,20-,22-,23+,24+,25+,26-,27+/m1/s1

Upstream product

• 133856-07-2 1α,3β-dihydroxy-22-tosyloxy-23,24-bisnorchola-5,7-diene 
• 107-82-4 i-pentyl bromide 
• 126771-82-2 C₃₃H₄₄O₉S 
• 65061-67-8 1α,2α-Epoxy-cholest-5-en-3β-ol 
• 26358-75-8 1α,3β-dihydroxycholest-5-ene 
• 35339-68-5 (5-Cholesten-1α,3β-diol)-diacetat 
• 41461-10-3 1α,3β-diacetoxycholesta-5,7-diene 

Downstream Products

• 41294-56-8 1α-hydroxyvitamin D3 

Relevant articles and documents

Continuous-flow synthesis of activated vitamin D3 and its analogues

An efficient, two-stage, continuous-flow synthesis of 1α,25-(OH) 2-vitamin D3 (activated vitamin D3) and its analogues was achieved. The developed method afforded the desired products in satisfactory yields using a high-intensity and economical light source, i.e., a high-pressure mercury lamp. In addition, our method required neither intermediate purification nor high-dilution conditions. The Royal Society of Chemistry 2012.

1-α-hydroxy vitamin D compounds and process for preparing same

The invention provides novel 1α-hydroxy vitamin D compounds and a method for their preparation from 1α-hydroxy-25-hydrogen cholesta-5,7-dienes by irradiation and isomerization techniques. The invention also includes the said 1α-hydroxy-25-hydrogen-cholesta-5,7-dienes and the corresponding cholest-5-enes. The new compounds may be obtained in a crystalline form substantially free from isomeric or other impurities arising from manufacture.

Synthesis of active forms of vitamin D. X. Synthesis of 1α hydroxyvitamin D3

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