442910-62-5

Basic information

• Product Name: tert-Butyl 7-methyl-1H-indole-1-carboxylate
• Synonyms: 1H-Indole-1-carboxylic acid, 7-Methyl-, 1,1-diMethylethyl ester;1-BOC-7-methylindole;tert-Butyl 7-methyl-1H-indole-1-carboxylate;7-Methyl-1H-indole, N-BOC protected
• CAS NO: 442910-62-5
• Molecular Formula: C₁₄H₁₇NO₂
• Molecular Weight: 231.29
• Product Categories: blocks;IndolesOxindoles
• Mol File: 442910-62-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 337.278°C at 760 mmHg
• Flash Point: 157.78°C
• Appearance: /
• Density: 1.064g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.537
• Storage Temp.: 2-8°C
• CAS DataBase Reference: tert-Butyl 7-methyl-1H-indole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 7-methyl-1H-indole-1-carboxylate(442910-62-5)
• EPA Substance Registry System: tert-Butyl 7-methyl-1H-indole-1-carboxylate(442910-62-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 442910-62-5(Hazardous Substances Data)

Usage

General Description

Tert-butyl 7-methyl-1H-indole-1-carboxylate is a chemical compound with the molecular formula C17H21NO2. It is an ester derivative of 7-methyl-1H-indole-1-carboxylic acid, containing a tert-butyl group attached to the carboxylate functional group. tert-Butyl 7-methyl-1H-indole-1-carboxylate is commonly used as a building block in organic synthesis for the preparation of various pharmaceuticals, agrochemicals, and other fine chemicals. It exhibits a strong, pleasant odor and is considered to be relatively stable under normal conditions. However, it should be handled and stored with appropriate care due to its potential hazards as a chemical reagent.

InChI:InChI=1/C14H17NO2/c1-10-6-5-7-11-8-9-15(12(10)11)13(16)17-14(2,3)4/h5-9H,1-4H3

Upstream product

• 85507-12-6 buta-2,3-dien-1-yl methanesulfonate 
• 79641-99-9 tert-butyl (3-methylfuran-2-yl)carbamate 
• 933-67-5 7-methyl-1H-indole 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 442910-45-4 tert-butyl 7-(bromomethyl)-1H-indole-1-carboxylate 
• 1256360-03-8 tert-butyl 7-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate 
• 914349-39-6 tert-butyl 3-bromo-7-methylindole-1-carboxylate 

Relevant articles and documents

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

Formation of 6-Azaindoles by Intramolecular Diels-Alder Reaction of Oxazoles and Total Synthesis of Marinoquinoline A

A new variant of the intramolecular Diels-Alder oxazole (IMDAO) cycloaddition that provides direct access to 6-azaindoles was developed. The IMDAO reaction was applied in a total synthesis of the aminophenylpyrrole-derived alkaloid marinoquinoline A, also

Substituted Indoles

The invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, th