4458-31-5 Usage
Description
N-(N-PROPYL)DIETHYLAMINE, also known as N-Propyldiethylamine, is a tertiary amine derived from propylamine, where the two amino hydrogens are replaced by ethyl groups. It is an organic compound with a wide range of applications across different industries due to its unique chemical properties.
Uses
Used in Chemical Synthesis:
N-(N-PROPYL)DIETHYLAMINE is used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its amine functional group allows for easy modification and reaction with other molecules, making it a versatile component in the creation of complex structures.
Used in Solvent Applications:
In the solvent industry, N-(N-PROPYL)DIETHYLAMINE is used as a solvent for various chemical reactions, particularly those involving organometallic compounds. Its ability to dissolve a wide range of substances and its relatively low toxicity compared to other solvents make it a preferred choice in certain applications.
Used in Catalyst Applications:
N-(N-PROPYL)DIETHYLAMINE is used as a catalyst in various chemical reactions, such as esterification, transesterification, and hydrogenation processes. Its basic nature and steric properties enable it to facilitate the reaction between substrates, leading to improved reaction rates and selectivity.
Used in the Pharmaceutical Industry:
N-(N-PROPYL)DIETHYLAMINE is used as an intermediate in the synthesis of various pharmaceutical compounds, including drugs for the treatment of central nervous system disorders, cardiovascular diseases, and other medical conditions. Its unique structure allows for the development of novel drug candidates with improved efficacy and safety profiles.
Used in the Agrochemical Industry:
In the agrochemical sector, N-(N-PROPYL)DIETHYLAMINE is used as a starting material for the synthesis of various pesticides, herbicides, and insecticides. Its ability to form stable complexes with other molecules enables the development of more effective and targeted agrochemical products.
Used in the Dye and Pigment Industry:
N-(N-PROPYL)DIETHYLAMINE is used as a precursor in the production of dyes and pigments, particularly those with specific color properties and stability. Its amine functionality allows for the creation of a wide range of colorants with diverse applications in the textile, plastics, and printing industries.
Check Digit Verification of cas no
The CAS Registry Mumber 4458-31-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,5 and 8 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4458-31:
(6*4)+(5*4)+(4*5)+(3*8)+(2*3)+(1*1)=95
95 % 10 = 5
So 4458-31-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H17N/c1-4-7-8(5-2)6-3/h4-7H2,1-3H3
4458-31-5Relevant articles and documents
Modular Attachment of Appended Boron Lewis Acids to a Ruthenium Pincer Catalyst: Metal-Ligand Cooperativity Enables Selective Alkyne Hydrogenation
Tseng, Kuei-Nin T.,Kampf, Jeff W.,Szymczak, Nathaniel K.
supporting information, p. 10378 - 10381 (2016/09/04)
A new series of bifunctional Ru complexes with pendent Lewis acidic boranes were prepared by late-stage modification of an active hydrogen-transfer catalyst. The appended boranes modulate the reactivity of a metal hydride as well as catalytic hydrogenations. After installing acidic auxiliary groups, the complexes become multifunctional and catalyze the cis-selective hydrogenation of alkynes with higher rates, conversions, and selectivities compared with the unmodified catalyst.
Continuous gas-phase hydroaminomethylation using supported ionic liquid phase catalysts
Schneider, Martin Johannes,Lijewski, Martin,Woelfel, Rene,Haumann, Marco,Wasserscheid, Peter
, p. 6996 - 6999 (2013/07/26)
Just SILP-ing through: Hydroaminomethylation of ethylene and diethylamine to diethylpropylamine is demonstrated as a continuous gas-phase reaction (see picture) using a supported ionic liquid phase (SILP) to immobilize the applied homogenous Rh-Xantphos catalyst. Highly selective and long-term stable (18 days) catalyst operation was obtained if the ionic liquid was of low basicity and lipophilicity combined with a porous activated carbon support. Copyright
Selective hydrogenation of amides using ruthenium/ molybdenum catalysts
Beamson, Graham,Papworth, Adam J.,Philipps, Charles,Smith, Andrew M.,Whyman, Robin
experimental part, p. 869 - 883 (2010/07/05)
Recyclable, heterogeneous bimetallic ruthenium/molybdenum catalysts, formed in situ from triruthenium dodecacarbonyl [Ru3(CO)12] and molybdenum hexacarbonyl [Mo(CO)6], are effective for the selective liquid phase hydrogenation of cyclohexylcarboxamide (CyCONH2) to cyclohexanemethylamine (CyCH2NH2), with no secondary or tertiary amine by-product formation. Variation of Mo:Ru composition reveals both synergistic and poisoning effects, with the optimum combination of conversion and selectivity at ca. 0.5, and total inhibition of catalysis evident at ≥1. Good amide conversions are noted within the reaction condition regimes 20100 bar hydrogen and 145-160°C. The order of reactivity of these catalysts towards reduction of different amide functional groups is primary > tertiary ? secondary. In situ HP-FT-IR spectroscopy confirms that catalyst genesis occurs during an induction period associated with decomposition of the organometallic precursors. Ex situ characterisation, using XRD, XPS and EDX-STEM, for active Mo:Ru compositions, has provided evidence for intimately mixed ca. 2.5-4 nm particles that contain metallic ruthenium, and molybdenum (in several oxidation states, including zero).
