450844-27-6

Basic information

• Product Name: 2-Bromo-6-cyano-3-methylpyridine
• Synonyms: 2-Bromo-6-cyano-3-methylpyridine;6-BroMo-5-Methylpicolinonitrile
• CAS NO: 450844-27-6
• Molecular Formula: C₇H₅BrN₂
• Molecular Weight: 197.03
• Mol File: 450844-27-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 303.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.61±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: -4.47±0.10(Predicted)
• CAS DataBase Reference: 2-Bromo-6-cyano-3-methylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-6-cyano-3-methylpyridine(450844-27-6)
• EPA Substance Registry System: 2-Bromo-6-cyano-3-methylpyridine(450844-27-6)

Safety Data

• Hazardous Substances Data: 450844-27-6(Hazardous Substances Data)

Usage

General Description

2-Bromo-6-cyano-3-methylpyridine is a chemical compound with the molecular formula C7H5BrN2. It is a derivative of pyridine and is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. This chemical is a yellowish to light brown crystalline solid with a melting point of 52-56°C. It is primarily used as a building block in the production of various compounds, including fungicides, herbicides, and insecticides. It is also used in the manufacturing of dyes, pigments, and other specialty chemicals. Additionally, 2-Bromo-6-cyano-3-methylpyridine is a versatile reagent in organic synthesis, particularly in the preparation of heterocyclic compounds. Due to its potential health hazards, proper handling and safety precautions should be observed when using this compound. Overall, 2-Bromo-6-cyano-3-methylpyridine is a valuable chemical with diverse applications in the pharmaceutical and chemical industries.

Upstream product

• 19230-57-0 2-bromo-3-methylpyridine 1-oxide 
• 7677-24-9 trimethylsilyl cyanide 
• 3430-17-9 2-bromo-3-picoline 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 
• 773837-37-9 sodium cyanide 
• 1620-77-5 5-methylpicolinonitrile 
• 2369-19-9 2-fluoro-5-methylpyridine 
• 159727-87-4 2-cyano-5-methylpyridine 1-oxide 

Downstream Products

• 450844-31-2 6-bromo-5-(((4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy)methyl)pyridine-2-carbonitrile 
• 450839-23-3 5-(((4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy)methyl)-6-(2,2-difluoro-1,3-benzodioxol-5-yl)pyridine-2-carbonitrile 
• 875293-80-4 6-bromo-5-methylpyridine-2-carboxamidine hydrochloride 
• 1211516-25-4 6-bromo-5-methyl-pyridine-2-carboxylic acid 
• 1415898-77-9 6-(3-chloro-phenyl)-5-methyl-pyridine-2-carboxylic acid 
• 952600-75-8 5,6-diethyl-3-[6-(4-fluorophenyl)-5-methylpyridin-2-yl]-1,2,4-triazine 
• 952600-76-9 3-[6-(4-fluorophenyl)-5-methylpyridin-2-yl]-5,6,7,8-tetrahydrobenzo[1,2,4]triazine 

Relevant articles and documents

NOVEL PYRIDINE DERIVATIVES

The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor

A series of 2-pyridone-containing imidazoline derivatives was synthesized and evaluated as neuropeptide Y Y5 receptor antagonists. Optimization of the 2-pyridone structure on the 2-position of the imidazoline ring led to identification of 1-(difluoromethy

Farnesyltransferase inhibitors

Substituted imidazoles and thiazoles having the formula are useful for inhibiting farnesyltransferase. Also disclosed are farnesyltransferase-inhibiting compositions and methods of inhibiting farnesyltransferase in a patient.