4533-89-5 Usage
Description
6alpha-fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate, also known as Flunisolide Acetate, is a synthetic fluorinated corticosteroid derived from the naturally occurring compound Prednisolone. It is characterized by its potent anti-inflammatory and immunosuppressive properties, making it a valuable compound in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
Flunisolide Acetate is used as an antiasthmatic agent for the treatment of asthma and other respiratory conditions. It works by reducing inflammation and suppressing the immune system, which helps to alleviate the symptoms of asthma and improve lung function.
Used in Anti-inflammatory Applications:
In addition to its use in asthma treatment, Flunisolide Acetate is also utilized in various anti-inflammatory applications. Its potent anti-inflammatory properties make it effective in managing inflammation associated with various conditions, such as allergies, skin disorders, and autoimmune diseases.
Used in Immunosuppressive Applications:
Due to its immunosuppressive effects, Flunisolide Acetate is employed in the management of autoimmune diseases and conditions that require the suppression of the immune system. It helps to prevent the body's immune response from attacking its own tissues, thereby reducing the severity of the disease and improving the patient's quality of life.
Check Digit Verification of cas no
The CAS Registry Mumber 4533-89-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,3 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4533-89:
(6*4)+(5*5)+(4*3)+(3*3)+(2*8)+(1*9)=95
95 % 10 = 5
So 4533-89-5 is a valid CAS Registry Number.
InChI:InChI=1/C26H33FO7/c1-13(28)32-12-20(31)26-21(33-23(2,3)34-26)10-16-15-9-18(27)17-8-14(29)6-7-24(17,4)22(15)19(30)11-25(16,26)5/h6-8,15-16,18-19,21-22,30H,9-12H2,1-5H3
4533-89-5Relevant articles and documents
NOVEL PROCESS FOR PREPARATION OF CORTICOSTEROIDS
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, (2018/03/25)
The present invention discloses a process for the preparation of pregnadiene derivatives having formula I, their stereoisomer and intermediate thereof. Formula I wherein each substituent is independently, R1 and R2 is hydrogen or C1 –C8straight, branched alkyl chain, saturated or unsaturated cycloalkyl; R3 is hydrogen or wherein R5 represents C1-C8 straight, branched alkyl chain or cycloalkyl; R4 is hydrogen or halogen; R6 is hydrogen or halogen;
FLUOROSTEROIDS. VII. SYNTHESIS AND BIOLOGICAL ACTIVITY OF DERIVATIVES OF 6&α-FLUORO-16&α,17&α-ISOPROPYLIDENEDIHYDROXYPREGNA-1,4-DIENE-11&β,21-DIOL-3,20-DIONE
Ryzhkova, V. M.,Gusarova, T. I.,Grinenko, G. S.,Gerasimova, M. L.,Bykova, T. M.,et al.
, p. 216 - 222 (2007/10/02)
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