4535-07-3

Basic information

• Product Name: 4-NITROINDANE-1,3-DIONE
• Synonyms: 4-NITROINDANE-1,3-DIONE;RARECHEM AR PA 0049;4-Nitro-1H-indene-1,3(2H)-dione;4-Nitro-1H-Indene-1,3(2H)-Dione(WXC02123);4-nitro-2,3-dihydro-1H-indene-1,3-dione
• CAS NO: 4535-07-3
• Molecular Formula: C₉H₅NO₄
• Molecular Weight: 191.14
• Product Categories: Indane/Indanone and Derivatives
• Mol File: 4535-07-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 128-130°
• Appearance: /
• CAS DataBase Reference: 4-NITROINDANE-1,3-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NITROINDANE-1,3-DIONE(4535-07-3)
• EPA Substance Registry System: 4-NITROINDANE-1,3-DIONE(4535-07-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 4535-07-3(Hazardous Substances Data)

Usage

Chemical Properties

bp 101-102°C (1torr) mp 55-59°C

Upstream product

• 39199-63-8 4-nitroindan-1,3-dione-2-carboxylic acid ethyl ester 
• 641-70-3 3-nitrophthalic acid anhydride 
• 1215220-51-1 1,1,3-tribromo-4-nitro-2,3-dihydro-1H-indene 
• 141-97-9 ethyl acetoacetate 
• 603-11-2 3-nitrophthalic acid 

Downstream Products

• 352000-78-3 7-amino-3-hydroxy-indan-1-one 
• 80960-26-5 2,2-dihydroxy-4-nitro-1H-indene-1,3(2H)-dione 

Relevant articles and documents

One-step synthesis of substituted isobenzofuran-1(3H)-ones and isobenzofuran-1,3-diones from indane derivatives in subcritical media

Molecular oxygen is one of the most attractive oxidants in organic synthesis because it is highly soluble in subcritical water. In this study, indane derivatives were oxidized to the corresponding isobenzofuran-1(3H)-one with molecular oxygen and isobenzofuran-1,3-dione with a mixture of molecular oxygen and H2O2 in subcritical water. This paper describes a simple, economic, environmentally benign,and general procedure that can be used for the synthesis of substituted isobenzofuran-1(3H)-ones and isobenzofuran-1,3-diones in only one step and without catalyst.

ANTIVIRAL 1,3-DI-OXO-INDENE COMPOUNDS

The invention provides compounds of Formula (I): as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.

Efficient synthesis of 7-amino-3-hydroxyindan-1-one

An efficient and reliable three-step synthesis of 7-amino-3-hydroxyindan-1- one (7) is described. Compound 7 is a versatile, three-dimensional, three-point scaffold that is useful for the construction of focused compound libraries. Copyright Taylor & Fran