4535-59-5

Basic information

• Product Name: ethyl 2-benzoyl-5-methylhex-4-enoate
• Synonyms: ethyl 2-benzoyl-5-methylhex-4-enoate
• CAS NO: 4535-59-5
• Molecular Weight: 260.333
• Mol File: 4535-59-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: ethyl 2-benzoyl-5-methylhex-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-benzoyl-5-methylhex-4-enoate(4535-59-5)
• EPA Substance Registry System: ethyl 2-benzoyl-5-methylhex-4-enoate(4535-59-5)

Safety Data

• Hazardous Substances Data: 4535-59-5(Hazardous Substances Data)

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 870-63-3 prenyl bromide 
• 98-86-2 acetophenone 
• 98-88-4 benzoyl chloride 

Downstream Products

• 4535-64-2 5-methyl-1-phenylhex-4-en-1-one 

Relevant articles and documents

Synthesis of 2,3,5,6-tetrasubstituted tetrahydropyrans via (3,5)-oxonium-ene reaction

An efficient method for the synthesis of 2,3,5,6-tetrasubstituted tetrahydropyrans has been developed from the reaction of aldehydes and ethyl 2-(1-hydroxyalkyl/hydroxy(phenyl)methyl)-5-methylhex-4-enoate using (3,5)-oxonium-ene reaction promoted by boron

Diastereoselective and Stereodivergent Synthesis of 2-Cinnamylpyrrolines Enabled by Photoredox-Catalyzed Iminoalkenylation of Alkenes

A photoredox-catalyzed iminoalkenylation of γ-alkenyl O-acyl oximes has been developed. Readily available alkenylboronic acids serve as alkenylation reagents, leading to densely functionalized pyrrolines. Both (E)- and (Z)-cinnamylpyrrolines are accessible depending on the reaction solvent. In dichloromethane, (E)-cinnamylpyrrolines are produced through a photoredox-mediated single-electron-transfer process. In tetrahydrofuran, (Z)-cinnamylpyrrolines are generated by photocatalytic contra-thermodynamic E-to-Z isomerization of (E)-cinnamylpyrrolines though an energy-transfer pathway. Two stereocenters are established with complete diastereoselectivity and only one diastereomer is isolated.

Photoredox Synthesis of Arylhydroxylamines from Carboxylic Acids and Nitrosoarenes

Hydroxylamines are found in biologically active compounds and serve as building blocks for the preparation of nitrogen-containing molecules. Here the direct conversion of carboxylic acids into the corresponding alkylhydroxylamines using organo-photoredox catalysis is reported. The process relies in the generation of alkyl radicals via photoinduced oxidation-decarboxylation and their following reaction with nitrosoarenes. We have successfully applied this method to the late-stage modification of complex and biologically active acids and applied it in novel radical cascade processes.