4535-64-2

Basic information

• Product Name: 4-Hexen-1-one,5-methyl-1-phenyl-
• CAS NO: 4535-64-2
• Molecular Weight: 188.269
• Mol File: 4535-64-2.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 4-Hexen-1-one,5-methyl-1-phenyl- (CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hexen-1-one,5-methyl-1-phenyl- (4535-64-2)
• EPA Substance Registry System: 4-Hexen-1-one,5-methyl-1-phenyl- (4535-64-2)

Safety Data

• Hazardous Substances Data: 4535-64-2(Hazardous Substances Data)

Upstream product

• 4528-19-2 5-Methyl-1-phenyl-4-hexen-1-ol 
• 352200-57-8 N-(5-methyl-1-phenyl-4-hexen-1-oxy)-4-(p-chlorophenyl)-thiazole-2(3H)-thione 
• 1110631-07-6 N-methoxy-N,5-dimethylhex-4-enamide 
• 591-51-5 phenyllithium 
• 65890-48-4 5-methyl-hex-4-enoyl chloride 
• 5636-65-7 5-methyl-4-hexenoic acid 
• 98-88-4 benzoyl chloride 
• 98-86-2 acetophenone 
• 2270-59-9 1-bromo-4-methylpent-3-ene 
• 6919-61-5 N-methoxy-N-methylbenzamide 
• 72863-20-8 α,α-Dimethylallyl phenyl sulfone 
• 70-11-1 α-bromoacetophenone 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 870-63-3 prenyl bromide 

Downstream Products

• 144121-61-9 (S)-5-methyl-1-phenyl-4-hexen-1-ol 
• 98-86-2 acetophenone 
• 830345-31-8 3,6-dimethyl-2-phenyl-1,5-heptadiene 
• 1027912-38-4 C₂₁H₃₆O₂Si 
• 1026528-24-4 C₂₀H₃₄O₂Si 
• 1027295-74-4 C₂₁H₃₆O₄Si 
• 643-93-6 3-methylbiphenyl 

Relevant articles and documents

Diastereoselective and Stereodivergent Synthesis of 2-Cinnamylpyrrolines Enabled by Photoredox-Catalyzed Iminoalkenylation of Alkenes

A photoredox-catalyzed iminoalkenylation of γ-alkenyl O-acyl oximes has been developed. Readily available alkenylboronic acids serve as alkenylation reagents, leading to densely functionalized pyrrolines. Both (E)- and (Z)-cinnamylpyrrolines are accessible depending on the reaction solvent. In dichloromethane, (E)-cinnamylpyrrolines are produced through a photoredox-mediated single-electron-transfer process. In tetrahydrofuran, (Z)-cinnamylpyrrolines are generated by photocatalytic contra-thermodynamic E-to-Z isomerization of (E)-cinnamylpyrrolines though an energy-transfer pathway. Two stereocenters are established with complete diastereoselectivity and only one diastereomer is isolated.

Iron-catalyzed carbonylative cyclization of γ,δ-unsaturated aromatic oxime esters to functionalized pyrrolines

Herein, a new method of iron-catalyzed carbonylative cyclization of γ,δ-unsaturated aromatic oxime esters to functionalized pyrrolines has been developed. By using readily available substrates, 32 examples of functionalized pyrrolines were prepared in moderate to good yields. Notably, examples of reduction and cycloaddition reactions of the obtained product were given as well. This journal is

A General Photocatalytic Route to Prenylation

Prenylation is an essential reaction on which nature relies to modify properties of molecules and build terpenoids, but remains a challenging chemical reaction. Aiming to capitalize on recent advances in photocatalysis to easily and cleanly generate a broad range of carbon based radicals, we have developed a prenyl transfer reagent that is captured by transiently generated radicals. The reagent can be made in bulk, is bench stable, and broadly applicable such that it can be used with existing photocatalytic methods with very few changes to reaction conditions. Ultimately, this provides a true drop-in solution for prenylation, expanding the scope of substrates that can be readily prenylated.