454451-28-6 Usage
Description
Boc-4-aminohexahydro-4h-azepine, also known as tert-Butyl Azepan-4-ylcarbamate, is a chemical compound with a unique structure consisting of a hexahydroazepine ring and a Boc-protected amine group. Boc-4-aminohexahydro-4h-azepine is known for its potential applications in various fields, particularly in the synthesis of pharmaceuticals and as antimicrobial agents.
Uses
Used in Pharmaceutical Industry:
Boc-4-aminohexahydro-4h-azepine is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and Boc-protected amine group make it a versatile building block for the development of new drugs with potential therapeutic applications.
Used in Antimicrobial Applications:
Boc-4-aminohexahydro-4h-azepine is used as a precursor in the preparation of cytosine derivatives, which serve as antimicrobial agents for the treatment of bacterial infections. These cytosine derivatives can help combat antibiotic-resistant bacteria and provide new treatment options for various infections.
Check Digit Verification of cas no
The CAS Registry Mumber 454451-28-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,4,4,5 and 1 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 454451-28:
(8*4)+(7*5)+(6*4)+(5*4)+(4*5)+(3*1)+(2*2)+(1*8)=146
146 % 10 = 6
So 454451-28-6 is a valid CAS Registry Number.
454451-28-6Relevant articles and documents
Side chain SAR of bicyclic β-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712
Chen, Helen,Blizzard, Timothy A.,Kim, Seongkon,Wu, Jane,Young, Katherine,Park, Young-Whan,Ogawa, Aimie M.,Raghoobar, Susan,Painter, Ronald E.,Wisniewski, Doug,Hairston, Nichelle,Fitzgerald, Paula,Sharma, Nandini,Scapin, Giovanna,Lu, Jun,Hermes, Jeff,Hammond, Milton L.
, p. 4267 - 4270 (2011/08/06)
The bridged monobactam β-lactamase inhibitor MK-8712 (1) effectively inhibits class C β-lactamases. Side chain N-alkylated and ring-opened analogs of 1 were prepared and evaluated for combination with imipenem to overcome class C β-lactamase mediated resi
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
-
, (2008/06/13)
The present invention relates to substituted xanthines of general formula wherein R1 to R4 are defined as in claim 1, the tautomers and the stereoisomers thereof, mixtures thereof, the prodrugs and the salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
