459-04-1 Usage
Description
4-Fluorophenylacetyl chloride is a clear yellow liquid that serves as an essential reagent in the field of organic synthesis. It is characterized by its acylating properties, which allow it to react with various compounds to form a range of products.
Uses
Used in Organic Synthesis:
4-Fluorophenylacetyl chloride is used as an acylating agent for the preparation of various organic compounds. Its ability to react with different substrates makes it a versatile tool in the synthesis of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Fluorophenylacetyl chloride is used to prepare monoacylated pyrazolidine by reacting with pyrazolidine. 4-Fluorophenylacetyl chloride has potential applications in the development of new drugs and therapeutic agents.
Used in Chemical Research:
4-Fluorophenylacetyl chloride is also utilized in the preparation of N-acyl isothiouronium chloride, which is an important intermediate in the synthesis of various chemical compounds. This application highlights the compound's role in advancing chemical research and development.
Used in the Synthesis of Bicyclic Pyrazolones and Dihydropyrrol-2-ones:
Furthermore, 4-Fluorophenylacetyl chloride may be employed in the synthesis of bicyclic pyrazolones and dihydropyrrol-2-ones. These compounds have potential applications in various fields, including pharmaceuticals, materials science, and agrochemicals, due to their unique chemical properties and structures.
Check Digit Verification of cas no
The CAS Registry Mumber 459-04-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,5 and 9 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 459-04:
(5*4)+(4*5)+(3*9)+(2*0)+(1*4)=71
71 % 10 = 1
So 459-04-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H6ClFO/c9-8(11)5-6-1-3-7(10)4-2-6/h1-4H,5H2
459-04-1Relevant articles and documents
Vibrational spectroscopic studies and computational study of 4-fluoro-N-(2′-hydroxy-4′-nitrophenyl)phenylacetamide
Mary, Y. Sheena,Yohannan Panicker,Varghese, Hema Tresa,Raju,Bolelli, Tugba Ertan,Yildiz, Ilkay,Granadeiro, Carlos M.,Nogueira, Helena I.S.
, p. 223 - 231 (2011)
Fourier-transform infrared (FT-IR) and FT-Raman spectra of 4-fluoro-N-(2′-hydroxy-4′-nitrophenyl)phenylacetamide were recorded and analyzed. A surface-enhanced Raman scattering (SERS) spectrum was recorded in silver colloid. The vibrational wavenumbers an
Novel quinoline derivative inhibitor
-
Paragraph 0755; 0758-0761; 0808; 0810-0812, (2020/03/12)
The invention provides a novel quinoline derivative inhibitor, which has a structure represented by the following general formula (I). According to the invention, the compound provided by the invention can selectively inhibit tyrosine kinase TAM family/an
Direct meta-C?H Perfluoroalkenylation of Arenes Enabled by a Cleavable Pyrimidine-Based Template
Brochetta, Massimo,Borsari, Tania,Bag, Sukdev,Jana, Sadhan,Maiti, Siddhartha,Porta, Alessio,Werz, Daniel B.,Zanoni, Giuseppe,Maiti, Debabrata
supporting information, p. 10323 - 10327 (2019/07/18)
The development of efficient and mild methods for the synthesis of organofluorine compounds is of foremost interest in various fields of chemistry. A direct pyrimidine-based selective meta-C?H perfluoroalkenylation of arenes involving several commercially
