459424-41-0

Basic information

• Product Name: 2-Fluoro-2-bromo-ethanol
• Synonyms: 2-Fluoro-2-bromo-ethanol;2-Bromo-2-fluoroethanol
• CAS NO: 459424-41-0
• Molecular Formula: C₂H₄BrFO
• Molecular Weight: 142.955
• Mol File: 459424-41-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 147℃
• Flash Point: 42℃
• Appearance: /
• Density: 1.831
• CAS DataBase Reference: 2-Fluoro-2-bromo-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-2-bromo-ethanol(459424-41-0)
• EPA Substance Registry System: 2-Fluoro-2-bromo-ethanol(459424-41-0)

Safety Data

• Hazardous Substances Data: 459424-41-0(Hazardous Substances Data)

Usage

General Description

2-Fluoro-2-bromo-ethanol is a chemical compound with the formula C2H4BrFO. It is a colorless liquid with a slightly sweet odor, and it is used as a reagent in organic synthesis. 2-Fluoro-2-bromo-ethanol is considered toxic, and exposure to it can cause irritation to the eyes, skin, and respiratory tract. It is also potentially harmful if ingested or inhaled. 2-Fluoro-2-bromo-ethanol is primarily used in the production of pharmaceuticals, agrochemicals, and other organic chemicals. It is important to handle this compound with care and follow safety procedures when working with it.

Upstream product

• 684-89-9 methyl 2-bromo-2-fluoroacetate 
• 401-55-8 ethyl bromofluoroacetate 

Relevant articles and documents

Method for preparing cis-1-amino-2-fluorocyclopropane

The invention provides a method for preparing cis-1-amino-2-fluorocyclopropane. A preparation process comprises 8 to 10 steps. A structural formula of the cis-1-amino-2-fluorocyclopropane is represented by a formula 1 shown in the description, and the form of benzene sulfonate or hydrochloride is relatively common. An important intermediate product, i.e., cis-fluoro-amine olefin 2 is synthesized. The method has the advantages that the consumption of diiodo-fluoromethane or dibromo-fluoromethane, which is expensive in price and causes heavy pollution in a raw material production process, is avoided; a cis triatomic ring is obtained through the cyclization of high-activity cis-olefin 2, and an absolute-configuration product can be obtained by only one-time resolution, so that the method has especially great advantages in the aspect of either economical efficiency of the raw materials, or the difficulty of resolution of isomers.