464900-21-8 Usage
General Description
TERT-BUTYL 8-HYDROXY-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE is a chemical compound with potential applications in the pharmaceutical and research industries. It is a tert-butyl ester derivative of 8-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylic acid, which is a heterocyclic compound with a quinoline ring system. This chemical may have antioxidant and neuroprotective properties, making it of interest for potential therapeutic applications. Additionally, it may also have uses as a biochemical research tool for studying the effects of quinoline derivatives on biological systems. Further research and testing are needed to fully understand the potential uses and effects of TERT-BUTYL 8-HYDROXY-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE.
Check Digit Verification of cas no
The CAS Registry Mumber 464900-21-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,4,9,0 and 0 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 464900-21:
(8*4)+(7*6)+(6*4)+(5*9)+(4*0)+(3*0)+(2*2)+(1*1)=148
148 % 10 = 8
So 464900-21-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H19NO3/c1-14(2,3)18-13(17)15-8-7-10-5-4-6-12(16)11(10)9-15/h4-6,16H,7-9H2,1-3H3
464900-21-8Relevant articles and documents
Synthesis and SAR of novel histamine H3 receptor antagonists
Jesudason, Cynthia D.,Beavers, Lisa S.,Cramer, Jeffrey W.,Dill, Joelle,Finley, Don R.,Lindsley, Craig W.,Stevens, F. Craig,Gadski, Robert A.,Oldham, Samuel W.,Pickard, R. Todd,Siedem, Christopher S.,Sindelar, Dana K.,Singh, Ajay,Watson, Brian M.,Hipskind, Philip A.
, p. 3415 - 3418 (2006)
The synthesis and biological evaluation of novel tetrahydroisoquinoline, tetrahydroquinoline, and tetrahydroazepine antagonists of the human and rat H3 receptors are described. The substitution around these rings as well as the nature of the substituent on nitrogen is explored. Several compounds with high affinity and selectivity for the human and rat H3 receptors are reported.
