74904-29-3

Basic information

• Product Name: 3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one
• Synonyms: 3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one;8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one
• CAS NO: 74904-29-3
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.19984
• Mol File: 74904-29-3.mol
• Article Data: 15

Chemical Properties

• Melting Point: 148-149 °C(Solv: benzene (71-43-2))
• Boiling Point: 439.8±45.0 °C(Predicted)
• Appearance: /
• Density: 1.159±0.06 g/cm3(Predicted)
• PKA: 14.77±0.20(Predicted)
• CAS DataBase Reference: 3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one(74904-29-3)
• EPA Substance Registry System: 3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one(74904-29-3)

Safety Data

• Hazardous Substances Data: 74904-29-3(Hazardous Substances Data)

Usage

General Description

3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one, also known as sabcomeline, is a chemical compound with the molecular formula C11H11NO2. It belongs to the class of isoquinolinones and is a potent and selective antagonist for the muscarinic acetylcholine receptor subtype M1. 3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one has been studied for its potential therapeutic effects in the treatment of schizophrenia, Alzheimer's disease, and other cognitive disorders. It is also being investigated for its potential as a treatment for drug addiction and other neurological disorders. Sabcomeline has shown promising results in preclinical studies, demonstrating its potential as a novel pharmacological agent for various neurological and psychiatric conditions.

Upstream product

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Downstream Products

• 73903-30-7 8-Methoxy-2-methyl-1,2,3,4-tetrahydroisochinolin 
• 81625-22-1 1-<4-(benzyloxy)benzyl>-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 81625-20-9 1-(3,4-dimethoxybenzyl)-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 81625-41-4 1-<4-(benzyloxy)benzyl>-2-(4-phenylbenzoyl)-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 81625-40-3 1-<4-(benzyloxy)benzyl>-2-(4-tert-butylbenzoyl)-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 81625-37-8 2-(4-tert-butylbenzoyl)-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 81625-39-0 2-(4-phenylbenzoyl)-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 81625-35-6 1-hydroxy-2-benzoyl-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 81625-36-7 2-benzoyl-8-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 1723-70-2 8-methoxyisoquinoline 
• 32999-37-4 1,2,3,4-tetrahydroisoquinoline-8-ol 
• 464900-21-8 8-hydroxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 81625-33-4 N-(benzenesulfonyl)-3,4-dihydro-3-methoxyisocarbostyril 
• 34146-68-4 8-methoxy-1,2,3,4-tetrahydroisoquinoline 

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