465615-69-4

Basic information

• Product Name: Methanone, (4-chlorophenyl)[1-methyl-2-[[1-(1-methylethyl)-4-piperidinyl]methoxy]-1 H-imidazol-5-yl]-
• CAS NO: 465615-69-4
• Molecular Formula: C20H26ClN3O2
• Molecular Weight: 375.898
• Mol File: 465615-69-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, (4-chlorophenyl)[1-methyl-2-[[1-(1-methylethyl)-4-piperidinyl]methoxy]-1 H-imidazol-5-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-chlorophenyl)[1-methyl-2-[[1-(1-methylethyl)-4-piperidinyl]methoxy]-1 H-imidazol-5-yl]-(465615-69-4)
• EPA Substance Registry System: Methanone, (4-chlorophenyl)[1-methyl-2-[[1-(1-methylethyl)-4-piperidinyl]methoxy]-1 H-imidazol-5-yl]-(465615-69-4)

Safety Data

• Hazardous Substances Data: 465615-69-4(Hazardous Substances Data)

Upstream product

• 122334-37-6 4-chloro-N-methoxy-N-methylbenzamide 
• 104-88-1 4-chlorobenzaldehyde 
• 6457-49-4 4-piperidinemethanol 
• 280774-03-0 (1-Isopropyl-piperidin-4-yl)-methanol 
• 465615-75-2 (4-Chlorophenyl)-[3-methyl-2-(propane-1-sulfonyl)-3H-imidazol-4-yl]-methanone 
• 807614-69-3 (2-chloro-3-methyl-3H-imidazol-4-yl)(4-chlorophenyl)methanone 
• 465615-73-0 (4-Chlorophenyl)-(3-methyl-2-propylsulfanyl-3H-imidazol-4-yl)-methanone 
• 465615-72-9 (4-Chlorophenyl)-(3-methyl-2-propylsulfanyl-3H-imidazol-4-yl)-methanol 
• 465613-31-4 (4-Chlorophenyl)-(2-mercapto-3-methyl-3H-imidazol-4-yl)-methanol 
• 122-01-0 4-chloro-benzoyl chloride 

Relevant articles and documents

Novel imidazole-based histamine H3 antagonists

A novel series of imidazole containing histamine H3 receptor ligands were investigated and found to be potent functional antagonists. After improving the stability of these molecules towards liver microsomes, these compounds were found to have

A scalable synthesis of a histamine H3 receptor antagonist

Starting from 1-methylimidazole, a concise, scalable, three-step synthesis of the title compound is described. The required 2-chloroimidazole was prepared in very good yield by halogen-metal exchange between the 2-lithio derivative and hexachloroethane.