Welcome to LookChem.com Sign In|Join Free

CAS

  • or

4665-63-8

Post Buying Request

4665-63-8 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

4665-63-8 Usage

General Description

2-(2-Benzothiazolylthio)ethanol is a chemical compound that belongs to the class of organic compounds known as benzothiazoles. These compounds contain a benzene fused to a thiazole ring. This specific chemical incorporates a sulfur and nitrogen atom, and it's connected to an ethanol chain, which means it has an alcohol functional group. It is expected to exist as a slightly yellowish to colorless viscous liquid. The chemical's potential uses and safety information are limited, thus it's important to handle it with appropriate safety measures. Routine risk and safety phrases may apply to this compound, suggesting it might be harmful if swallowed, inhaled, or comes into contact with skin.

Check Digit Verification of cas no

The CAS Registry Mumber 4665-63-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,6 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4665-63:
(6*4)+(5*6)+(4*6)+(3*5)+(2*6)+(1*3)=108
108 % 10 = 8
So 4665-63-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NOS2/c11-5-6-12-9-10-7-3-1-2-4-8(7)13-9/h1-4,11H,5-6H2

4665-63-8 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Aldrich

  • (454451)  2-(2-Benzothiazolylthio)ethanol  95%

  • 4665-63-8

  • 454451-5G

  • 683.28CNY

  • Detail

4665-63-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(1,3-benzothiazol-2-ylsulfanyl)ethanol

1.2 Other means of identification

Product number -
Other names 2-(2-Hydroxyethylmercapto)benzothiazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4665-63-8 SDS

4665-63-8Synthetic route

2-thioxo-3H-1,3-benzothiazole
149-30-4

2-thioxo-3H-1,3-benzothiazole

2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

Conditions
ConditionsYield
With oxirane; 1,4-dioxane at 95 - 105℃;
With 3,6,9-trioxaundecane at 125 - 130℃;
sodium 2-mercaptobenzothiazole
2492-26-4

sodium 2-mercaptobenzothiazole

2-chloro-ethanol
107-07-3

2-chloro-ethanol

2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

Conditions
ConditionsYield
With water
With ethanol
potassium 2-mercaptobenzothiazolate
7778-70-3

potassium 2-mercaptobenzothiazolate

2-chloro-ethanol
107-07-3

2-chloro-ethanol

2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

Conditions
ConditionsYield
With water
With ethanol
2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

2-chloro-ethanol
107-07-3

2-chloro-ethanol

2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

Iodoethanol
624-76-0

Iodoethanol

2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

Conditions
ConditionsYield
Stage #1: 2-Mercaptobenzothiazole With potassium carbonate In methanol at 30℃; for 0.25h;
Stage #2: Iodoethanol In methanol at 30℃; for 20.25h; Heating / reflux;
ethylene glycol
107-21-1

ethylene glycol

2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 4h; Inert atmosphere;
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

acrylic acid
79-10-7

acrylic acid

(2-(2-benzothiazolylthio)ethyl)acrylate
39667-72-6

(2-(2-benzothiazolylthio)ethyl)acrylate

Conditions
ConditionsYield
With 2-chloro-1-methyl-pyridinium iodide; triethylamine In dichloromethane at 20℃; for 24h;96%
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

1-(1-isocyanato-1-methylethyl)-3-(1-methylethenyl)benzene
2094-99-7

1-(1-isocyanato-1-methylethyl)-3-(1-methylethenyl)benzene

C22H24N2O2S2
644985-60-4

C22H24N2O2S2

Conditions
ConditionsYield
dibutyltin dilaurate In toluene at 80℃; for 4.16667h;95%
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

4-Nitrophthalonitrile
31643-49-9

4-Nitrophthalonitrile

4-(2-(2-benzothiazolylthio)ethoxy)phthalonitrile
1415353-65-9

4-(2-(2-benzothiazolylthio)ethoxy)phthalonitrile

Conditions
ConditionsYield
Stage #1: 2-(2-benzothiazolylthio)ethanol; 4-Nitrophthalonitrile In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere;
Stage #2: With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 74h; Inert atmosphere;
78%
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

2-(benzo[d]thiazol-2-ylsulfonyl)ethan-1-ol
189579-73-5

2-(benzo[d]thiazol-2-ylsulfonyl)ethan-1-ol

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 20℃;77%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 20℃; for 20h; Inert atmosphere;8.9 g
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

2-benzothiazolyl 2-hydroxyethyl sulfoxide
80142-39-8

2-benzothiazolyl 2-hydroxyethyl sulfoxide

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 20℃; Inert atmosphere;70%
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

ethyl acetoacetate
141-97-9

ethyl acetoacetate

2-(1,3-benzothiazol-2-ylthio)ethyl 3-oxobutanoate
1256945-15-9

2-(1,3-benzothiazol-2-ylthio)ethyl 3-oxobutanoate

Conditions
ConditionsYield
In toluene for 22h; Reflux;59%
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

2-Ethylhexanoic acid
149-57-5

2-Ethylhexanoic acid

2-ethyl-hexanoic acid-(2-benzothiazol-2-ylmercapto-ethyl ester)
101599-05-7

2-ethyl-hexanoic acid-(2-benzothiazol-2-ylmercapto-ethyl ester)

Conditions
ConditionsYield
With toluene-4-sulfonic acid; toluene
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

A

1,4-Dithiane
505-29-3

1,4-Dithiane

B

2(3H)-Benzothiazolone
934-34-9

2(3H)-Benzothiazolone

Conditions
ConditionsYield
at 125 - 200℃;
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

2(3H)-Benzothiazolone
934-34-9

2(3H)-Benzothiazolone

Conditions
ConditionsYield
With dihydrogen peroxide
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

2,3-dihydro-benzo[d]thiazolo[2,3-b]thiazolylium; chloride
2768-98-1

2,3-dihydro-benzo[d]thiazolo[2,3-b]thiazolylium; chloride

Conditions
ConditionsYield
With thionyl chloride; chloroform
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid
55750-53-3

2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid

C19H20N2O4S2
644985-62-6

C19H20N2O4S2

Conditions
ConditionsYield
With sulfuric acid In toluene at 80 - 140℃; for 11h;
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

triphenylphosphine
603-35-0

triphenylphosphine

(S)-3-(4-hydroxyphenyl)-2-pyrrol-1-yl-propionic acid methyl ester
116763-11-2

(S)-3-(4-hydroxyphenyl)-2-pyrrol-1-yl-propionic acid methyl ester

(S)-3-{4-[2-(Benzothiazol-2-ylsulfanyl)-ethoxy]-phenyl}-2-pyrrol-1-yl-propionic acid methyl ester

(S)-3-{4-[2-(Benzothiazol-2-ylsulfanyl)-ethoxy]-phenyl}-2-pyrrol-1-yl-propionic acid methyl ester

Conditions
ConditionsYield
With diisopropyl (E)-azodicarboxylate In tetrahydrofuran; ethyl acetate
2-(2-benzothiazolylthio)ethanol
4665-63-8

2-(2-benzothiazolylthio)ethanol

C15H23NO3S2Si
1449477-31-9

C15H23NO3S2Si

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 20 h / 0 - 20 °C / Inert atmosphere
2: dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere
View Scheme

4665-63-8Relevant articles and documents

Leaching of 2-(2-hydroxyethylmercapto)benzothiazole into contents of disposable syringes

Petersen,Vine,Ashley,Nation

, p. 1139 - 1143 (1981)

-

HYDROXYALKYL DERIVATIVES OF BIOLOGICALLY ACTIVE COMPOUNDS

-

Page/Page column 13, (2010/02/14)

Hydroxyalkyl derivatives of biologically active compounds represented by the formula VII wherein R2 = H, CI-12 alkyl, C6-12 aryl, or -OH and D = Biologically active agent having functional groups such as Formula (a) epoxy or aziridine and Z' = Formula (b) L= spacer comprising (un)substituted alkyl, hydroxyalkyl or alkoxy alkyl with the condition that the carbon chain length contains 2 to 6 carbon atoms when Z' = Formula (c) and pharmaceutically acceptable acid addition salts and enantiomers thereof Also process for the synthesis of compounds of the Formula VII and pharmaceutically acceptable acid addition salts and enantiomers thereof comprising condensation of the biologically active agents having functional groups such as Formula (d) epoxy or azifidine with substituted alkyl derivatives under alkaline conditions, at 20 - 80°C, in an organic solvent.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 4665-63-8