470716-52-0

Basic information

• Product Name: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane
• Synonyms: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane;2-[[(4-chlorophenyl)thio]Methyl]-1,4-difluorobenzene
• CAS NO: 470716-52-0
• Molecular Formula: C₁₃H₉ClF₂S
• Molecular Weight: 270.7253664
• Mol File: 470716-52-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane(470716-52-0)
• EPA Substance Registry System: (4-chlorophenyl)(2,5-difluorobenzyl)sulfane(470716-52-0)

Safety Data

• Hazardous Substances Data: 470716-52-0(Hazardous Substances Data)

Usage

General Description

The chemical compound "(4-chlorophenyl)(2,5-difluorobenzyl)sulfane" is a sulfane compound with a 4-chlorophenyl group bonded to a (2,5-difluorobenzyl) group. Sulfane compounds are sulfur analogs of organic peroxides and are known for their potential biological and pharmaceutical applications. This specific compound may have potential uses in pharmaceutical development or as a chemical intermediate in organic synthesis. Its unique structure and potential reactivity make it a subject of interest for further research in the fields of chemistry and pharmacology.

Upstream product

• 85117-99-3 2-(bromomethyl)-1,4-difluorobenzene 
• 106-54-7 p-Chlorothiophenol 
• 75853-20-2 2,5-difluoro-benzyl alcohol 

Downstream Products

• 470716-51-9 2-[[(4-chlorophenyl)sulfonyl]methyl]-1,4-difluorobenzene 
• 471904-46-8 C₁₉H₁₈ClF₂NO₃S 
• 471905-38-1 C₂₂H₂₃ClF₂N₂O₄S 
• 471905-47-2 C₂₃H₂₅ClF₂O₄S 
• 471903-70-5 C₂₄H₂₆ClF₂NO₄S 
• 471903-19-2 5-(4-chloro-benzenesulfonyl)-5-(2,5-difluoro-phenyl)-2-hydroxy-cyclohex-1-enecarboxylic acid methyl ester 
• 471903-67-0 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid ethyl ester 
• 471903-66-9 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexylidene]-acetic acid ethyl ester 
• 471903-69-2 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid 
• 471903-41-0 trans-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 471905-53-0 cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanol 
• 558464-31-6 (RS)-tert-butyl 4-[(4-chlororbenzenesulfonyl)-(2,5-difluorophenyl)methyl]-piperidine-1-carboxylate 
• 558464-29-2 4-[[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl)methyl]tetrahydrothiopyrane 
• 852312-96-0 5-(4-chloro-benzenesulfonyl)-5-(2,5-difluoro-phenyl)-2-oxo-cyclohexanecarboxylic acid methyl ester 

Relevant articles and documents

A practical synthesis of a γ-secretase inhibitor

(Chemical Equation Presented) A practical and scaleable synthesis of the γ-secretase inhibitor 1 is reported. The inhibitor consists of a central trisubstituted cyclohexane core with appended propionic acid, 2,5-difluorophenyl, and 4-chlorophenylsulfonyl

HETEROCYCLIC METHYL SULFONE DERIVATIVE

Provided is a compound capable of inhibiting production or secretion of β amyloid protein. A compound represented by the following formula (1): (wherein, R1 represents a heterocyclic group which may have a substituent, R2 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a substituent, R3 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a substituent, R4 represents a hydrogen atom or a C1-6 alkyl group, and X represents -S-,-SO- or -SO2-) an N-oxide or S-oxide thereof; a salt thereof; or a solvate thereof; and a medicament containing any of them.

The new cyclohexylpropionic sulfone

Novel sulphones of formula I are disclosed: The compounds modulate the processing of amyloid precursor protein by gamma-secretase, and hence are useful in the treatment or prevention of Alzheimer's disease.