4753-02-0 Usage
General Description
2'-Bromo-2'-deoxy-D-uridine, also known as BrdU, is a synthetic nucleoside analogue that is commonly used in molecular biology to label and detect proliferating cells. It is structurally similar to thymidine and can be incorporated into the DNA of dividing cells during replication. The bromine atom in BrdU can be detected using specific antibodies in immunohistochemical assays, making it a valuable tool for studying cell proliferation and DNA replication. BrdU is also used in neuroscience to study neurogenesis and in cancer research to investigate tumor growth and metastasis. However,
Check Digit Verification of cas no
The CAS Registry Mumber 4753-02-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,5 and 3 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4753-02:
(6*4)+(5*7)+(4*5)+(3*3)+(2*0)+(1*2)=90
90 % 10 = 0
So 4753-02-0 is a valid CAS Registry Number.
4753-02-0Relevant articles and documents
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Codington et al.
, p. 5030 (1961)
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A Convenient Synthesis of 2'-Deoxyuridine
Bhat, K. S.,Rao, A. S.
, p. 678 - 679 (2007/10/02)
Reaction of uridine (2) with 2-acetoxybenzoyl bromide (10) furnishes 3',5'-di-O-acetyl-2'-bromo-2'-deoxyuridine (4).Reaction of 2 with 2-acetoxy-5-nitrobenzoyl chloride (11) furnishes 3',5'-di-O-acetyl-2'-chloro-2'-deoxyuridine (5).The transformation of 4 and 5 to 2'-deoxyuridine (1) is known .