478-29-5

Basic information

• Product Name: 1,5,6-trihydroxy-2-methyl-anthracene-9,10-dione
• Synonyms: 1,5,6-trihydroxy-2-methyl-anthracene-9,10-dione;9,10-Anthracenedione, 1,2,5-trihydroxy-6-methyl-;Aids098144;Aids-098144
• CAS NO: 478-29-5
• Molecular Formula: C₁₅H₁₀O₅
• Molecular Weight: 0
• Mol File: 478-29-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 494.8°Cat760mmHg
• Flash Point: 267.1°C
• Appearance: /
• Density: 1.583g/cm³
• Vapor Pressure: 2.05E-10mmHg at 25°C
• Refractive Index: 1.744
• CAS DataBase Reference: 1,5,6-trihydroxy-2-methyl-anthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5,6-trihydroxy-2-methyl-anthracene-9,10-dione(478-29-5)
• EPA Substance Registry System: 1,5,6-trihydroxy-2-methyl-anthracene-9,10-dione(478-29-5)

Safety Data

• Hazardous Substances Data: 478-29-5(Hazardous Substances Data)

Usage

Family

Anthraquinone

Biological activities

Wide range of biological activities

Physical state

Orange to brown crystalline solid at room temperature

Industrial applications

Textile dyeing and printing

Antioxidant properties

Exhibits antioxidant properties

Potential effects

Anti-inflammatory and anticancer effects

Organic synthesis

Investigated for potential use in organic synthesis

Pharmaceutical compounds

Precursor for the production of pharmaceutical compounds

InChI:InChI=1/C15H10O5/c1-6-2-3-7-10(12(6)17)13(18)8-4-5-9(16)15(20)11(8)14(7)19/h2-5,16-17,20H,1H3

Downstream Products

• 60450-21-7 1,5-dihydroxy-2-methyl-6-O-β-primeverosyl-9,10-anthracenedione 
• 144-62-7 oxalic acid 
• 613-12-7 2-methylanthracene 
• 69232-87-7 1,2,5-tris-benzoyloxy-6-methyl-anthraquinone 

Relevant articles and documents

Anthraquinones from Neonauclea calycina and their inhibitory activity against DNA topoisomerase II

In a series of searches for DNA topoisomerase II inhibitors from naturally occurring compounds, a wood extract of Neonauclea calycina MERR. (Rubiaceae) showed a moderate effect in vitro. Purification of the extract resulted in the isolation of seven known anthraquinones. The structures were characterized as damnacanthal, rubindin 1-methyl ether, nordamnacanthal, morindone, damnacanthol, lucidin 3-O-primeveroside and morindone 6-O- primeveroside by spectral analysis, respectively. Damnacanthal and morindone showed an intensive inhibitory effect against topoisomerase II (IC50: 20 μg/ml and 21 μg/ml).