478258-81-0

Basic information

• Product Name: 5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE
• Synonyms: 5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE;5-BROMO-2-(2,5-DIMETHYL-PYRROL-1-YL)-PYRIMIDINE
• CAS NO: 478258-81-0
• Molecular Formula: C₁₀H₁₀BrN₃
• Molecular Weight: 252.11
• Mol File: 478258-81-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 66-68°
• Boiling Point: 402.5°C at 760 mmHg
• Flash Point: 197.2°C
• Appearance: /
• Density: 1.50
• Vapor Pressure: 1.09E-06mmHg at 25°C
• Refractive Index: 1.645
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE(478258-81-0)
• EPA Substance Registry System: 5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE(478258-81-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 478258-81-0(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyrimidine is a chemical compound with a molecular formula C10H10BrN3. It is a pyrimidine derivative with a bromine atom and a pyrrole ring in its structure. 5-BROMO-2-(2,5-DIMETHYL-1H-PYRROL-1-YL)PYRIMIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and functional materials. It has potential applications in the development of drugs for various therapeutic uses, including anti-cancer and anti-inflammatory properties. Additionally, it may also be used as a building block in organic synthesis for the preparation of various complex molecules. Overall, 5-Bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyrimidine is a versatile chemical with diverse potential applications in the field of drug discovery and organic synthesis.

InChI:InChI=1/C10H10BrN3/c1-7-3-4-8(2)14(7)10-12-5-9(11)6-13-10/h3-6H,1-2H3

Upstream product

• 7752-82-1 5-bromo-2-aminopyrimidine 
• 110-13-4 2,5-hexanedione 

Downstream Products

• 1083329-35-4 2-N-(2,5-dimethylpyrrolo)-5-benzyloxypyrimidine 
• 1011300-79-0 6-{1-[4-[2-(2,5-dimethyl-1H-pyrrol-1-yl)pyrimidin-5-yl]phenyl]-1,2-dimethylpropyl}pyridin-3-ol 

Relevant articles and documents

Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis

Herein we report an investigation of the efficacy of pyridine and pyrimidine analogs of acetaminophen (ApAP) as peroxyl radical-trapping antioxidants and inhibitors of enzyme-catalyzed lipid peroxidation by cyclooxygenases (COX) and lipoxygenases (LOX). I

A simple Cu-catalyzed coupling approach to substituted 3-pyridinol and 5-pyrimidinol antioxidants

(Chemical Equation Presented) A convenient approach to 3-pyridinols and 5-pyrimidinols via a two-step Cu-catalyzed benzyloxylation/catalytic hydrogenation sequence is presented. The corresponding 3-pyridinamines and 5-pyrimidinamines can be prepared in an analogous sequence utilizing benzylamine in lieu of benzyl alcohol. The radical-scavenging ability of these derivatives are preliminarily explored and reveal that the increased acidities of the pyridinols and pyrimidinols render them susceptible to more significant kinetic solvent effects when compared to phenols.

DIPHENYL SUBSTITUTED ALKANES

The instant invention provides compounds of Formula I which are 5-lipoxygenase activating protein inhibitors: formula (I). Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.