48141-64-6 Usage
Description
[R-(R,S)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol is a complex chiral molecule with a benzyl alcohol group and an ethylmethylaminoethyl group attached to a chiral carbon. It is often utilized in pharmaceutical and chemical research due to its unique structural properties and potential applications in the synthesis of other organic compounds.
Uses
Used in Pharmaceutical Research:
[R-(R,S)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol is used as a precursor in the pharmaceutical industry for the synthesis of various organic compounds. Its chiral nature makes it particularly valuable for asymmetric synthesis, which is crucial in the development of enantiomerically pure drugs with desired biological activities.
Used in Chemical Research:
In the field of chemical research, [R-(R,S)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol serves as a key intermediate in the synthesis of complex organic molecules. Its unique structure allows for further functionalization and modification, enabling the creation of novel compounds with potential applications in various industries.
Used in Synthesis of Chiral Compounds:
Due to its chiral nature, [R-(R,S)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol is used as a building block in the synthesis of chiral compounds. These chiral compounds have applications in various fields, including pharmaceuticals, agrochemicals, and materials science, where they can exhibit different biological activities based on their stereochemistry.
Used in Drug Delivery Systems:
[R-(R,S)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol can be employed in the development of drug delivery systems, where its chiral properties may contribute to the selective targeting of specific biological receptors or the enhancement of drug solubility and bioavailability.
Used in Analytical Chemistry:
[R-(R,S)]-alpha-[1-(ethylmethylamino)ethyl]benzyl alcohol's unique structure and chiral properties make it a valuable tool in analytical chemistry for the development of chiral stationary phases for chromatography, which are essential for the separation and analysis of enantiomers in various samples.
Check Digit Verification of cas no
The CAS Registry Mumber 48141-64-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,8,1,4 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 48141-64:
(7*4)+(6*8)+(5*1)+(4*4)+(3*1)+(2*6)+(1*4)=116
116 % 10 = 6
So 48141-64-6 is a valid CAS Registry Number.
48141-64-6Relevant articles and documents
-
Dehmlow,E.V. et al.
, p. 363 - 366 (1977)
-
The Reductive Cleavage of Cyclic Aminol Ethers to N,N-Dialkylamino-derivatives: Modifications to the Eschweiler-Clarke Procedure
Page, Philip C. Bulman,Heaney, Harry,Rassias, Gerasimos A.,Reignier, Serge,Sampler, Edward P.,Talib, Salem
, p. 104 - 106 (2007/10/03)
The reductive cleavage of cyclic aminol ethers to give N-alkylamino-derivatives in very high yields can be achieved using chlorotrimethylsilane in the presence of sodium cyanoborohydride: in the case of cyclic aminol ethers derived from formaldehyde the Eschweiler-Clarke reaction can be carried out in formic acid heated under reflux in the absence of formaldehyde.
Reactions of (-)-Ephedrine, (+)-Norpseudoephedrine and Derivatives with N,N-Dimethylacetamid-dimethylacetal and N,N-Dimethylformamid-dimethylacetal
Koehl, M,Spreitzer, H.,Fleischhacker, W.
, p. 911 - 918 (2007/10/02)
The reactivity of (-)-ephedrine (2) and (+)-norpseudoephedrine (3) towards the amid-acetals 1 a/b has been studied.Both 2 and 3 were acetylated resp. formylated at first at the amino group.Nevertheless, derivatives of 2 and 3 possessing a trisubstituted amino group react with 1 a in a sigmatropic rearrangement to ortho substituted dimethylcarbamoylmethyl derivatives.By subsequent reduction with lithiumaluminiumhydride the aromatic compounds 8, 13, and 18 with two aminoethyl groups are easily available.In contrast to these results 1 b did not furnish any rearrangement products. Keywords. (-)-Ephedrine; (+)-Norpseudoephedrine; N,N-Dimethylacetamid-dimethylacetal; N,N-Dimethylformamid-dimethylacetal; Sympathomimetic effects; Sigmatropic rearrangements.
