48141-77-1Relevant articles and documents
Stereocontrolled Syntheses of Mannich Bases and γ-Amino Alcohols
Risch, Nikolaus,Esser, Achim
, p. 233 - 238 (2007/10/02)
The reaction of enantiomerically pure SMP enamines 2 with iminium tetrachloroaluminates 3 yields optically active Mannich bases 4.Diastereoselective reduction of 4 gives γ-amino alcohols 5 with the desired configuration. Key Words: Mannich bases / Enamines / Iminium salts / γ-Amino alcohols