4817-67-8

Basic information

• Product Name: L-Phenylalanine, N-[N-(trifluoroacetyl)-L-valyl]-, methyl ester
• CAS NO: 4817-67-8
• Molecular Formula: C17H21F3N2O4
• Molecular Weight: 374.36
• Mol File: 4817-67-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[N-(trifluoroacetyl)-L-valyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[N-(trifluoroacetyl)-L-valyl]-, methyl ester(4817-67-8)
• EPA Substance Registry System: L-Phenylalanine, N-[N-(trifluoroacetyl)-L-valyl]-, methyl ester(4817-67-8)

Safety Data

• Hazardous Substances Data: 4817-67-8(Hazardous Substances Data)

Upstream product

• 72-18-4 L-valine 
• 349-00-8 N-trifluoroacetyl-L-valine 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 2357-39-3 2-trifluoromethyl-4-isopropyl-Δ³-oxazolin-5-one 
• 78395-22-9 methyl ester of N-trifluoroacetyldehydrovalylphenylalanine 
• 110582-75-7 2-trifluoromethyl-4-isopropylidene-Δ²-oxazolin-5-one 

Relevant articles and documents

The: Ortho -substituent on 2,4-bis(trifluoromethyl)phenylboronic acid catalyzed dehydrative condensation between carboxylic acids and amines

2,4-Bis(trifluoromethyl)phenylboronic acid is a highly effective catalyst for dehydrative amidation between carboxylic acids and amines. Mechanistic studies suggest that a 2:2 mixed anhydride is expected to be the only active species, and the ortho-substituent of boronic acid plays a key role in preventing the coordination of amines to the boron atom of the active species, thus accelerating the amidation. This catalyst works for α-dipeptide synthesis.

DIASTEREOSELECTIVE HYDROGENATION OF METHYL ESTERS OF TRIFLUOROACETYLDEHYDROPHENYLALANYL DIPEPTIDES AND TRIFLUOROACETYLDEHYDROVALYL DIPEPTIDES

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