4836-52-6 Usage
Description
(2S)-2-amino-3-(3H-imidazol-4-yl)propan-1-ol, also known as an amino alcohol, is a compound that features a propanol structure substituted by an imidazol-4-yl group at the 3rd position and an amino group at the 2nd position. The 2S stereoisomer indicates the specific arrangement of the atoms in the molecule, which is crucial for its properties and potential applications.
Uses
Used in Pharmaceutical Industry:
(2S)-2-amino-3-(3H-imidazol-4-yl)propan-1-ol is used as a pharmaceutical compound for its potential therapeutic applications. The unique structure of this molecule allows it to interact with various biological targets, making it a promising candidate for the development of new drugs.
Used in Chemical Synthesis:
(2S)-2-amino-3-(3H-imidazol-4-yl)propan-1-ol can be used as a building block or intermediate in the synthesis of more complex molecules, such as pharmaceuticals, agrochemicals, or other specialty chemicals. Its versatile structure enables it to be a valuable component in the creation of novel compounds with specific properties and functions.
Used in Research and Development:
This amino alcohol is also utilized in research and development settings to study its interactions with various biological systems and to explore its potential applications in different fields. The 2S stereoisomer's specific arrangement of atoms can provide insights into the effects of stereochemistry on molecular recognition and activity.
Check Digit Verification of cas no
The CAS Registry Mumber 4836-52-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,3 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4836-52:
(6*4)+(5*8)+(4*3)+(3*6)+(2*5)+(1*2)=106
106 % 10 = 6
So 4836-52-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H11N3O/c7-5(3-10)1-6-2-8-4-9-6/h2,4-5,10H,1,3,7H2,(H,8,9)/t5-/m0/s1
4836-52-6Relevant articles and documents
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Lintermans,Bearden
, p. 18 (1972)
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Hit to lead studies on (hetero)arylpyrimidines-Agonists of the canonical Wnt-β-catenin cellular messaging system
Gilbert, Adam M.,Bursavich, Matthew G.,Alon, Nippa,Bhat, Bheem M.,Bex, Frederick J.,Cain, Michael,Coleburn, Valerie,Gironda, Virginia,Green, Paula,Hauze, Diane B.,Kharode, Yogendra,Krishnamurthy, Girija,Kirisits, Matthew,Lam, Ho-Sun,Liu, Yao-Bin,Lombardi, Sabrina,Matteo, Jeanne,Murrills, Richard,Robinson, John A.,Selim, Sally,Sharp, Michael,Unwalla, Raymond,Varadarajan, Usha,Zhao, Weiguang,Yaworsky, Paul J.
experimental part, p. 366 - 370 (2010/04/06)
A series of (hetero)arylpyrimidines agonists of the Wnt-β-catenin cellular messaging system have been prepared. These compounds show activity in U2OS cells transfected with Wnt-3a, TCF-luciferase, Dkk-1 and tk-Renilla. Selected compounds show minimal GSK-3β inhibition indicating that the Wnt-β-catenin agonism activity most likely comes from interaction at Wnt-3a/Dkk-1. Two examples 1 and 25 show in vivo osteogenic activity in a mouse calvaria model. One example 1 is shown to activate non-phosphorylated β-catenin formation in bone.