4842-43-7

Basic information

• Product Name: 2-methyl-1,3-diphenylpropan-1-one
• CAS NO: 4842-43-7
• Molecular Formula: C₁₆H₁₆O
• Molecular Weight: 224.2976
• Mol File: 4842-43-7.mol
• Article Data: 56

Chemical Properties

• Boiling Point: 360.1°C at 760 mmHg
• Flash Point: 155.5°C
• Density: 1.042g/cm³
• Vapor Pressure: 2.28E-05mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: 2-methyl-1,3-diphenylpropan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1,3-diphenylpropan-1-one(4842-43-7)
• EPA Substance Registry System: 2-methyl-1,3-diphenylpropan-1-one(4842-43-7)

Safety Data

• Hazardous Substances Data: 4842-43-7(Hazardous Substances Data)

Upstream product

• 4258-37-1 1,3-diphenyl-2-methylpropene-3-one 
• 555-54-4 diphenylmagnesium 
• 80-62-6 methacrylic acid methyl ester 
• 93-55-0 1-phenyl-propan-1-one 
• 1083-30-3 dihydrochalcone 
• 94-41-7 benzalacetophenone 
• 67-56-1 methanol 
• 4663-33-6 1,3-diphenyl-3-hydroxypropene 
• 4393-06-0 1-Phenyl-2-propen-1-ol 
• 100-51-6 benzyl alcohol 
• 14182-01-5 (2E)-2-methyl-1,3-diphenylprop-2-en-1-one 
• 100-42-5 styrene 
• 100-52-7 benzaldehyde 
• 1074-12-0 phenylglyoxal hydrate 

Downstream Products

• 327619-20-5 thiophosphoric acid S-(1-benzyl-1-methyl-2-oxo-2-phenyl-ethyl) ester O,O'-diisopropyl ester 
• 252975-30-7 selenophosphoric acid Se-(1-benzoyl-1-methyl-2-oxo-2-phenylethyl) ester O,O-diethyl ester 
• 252975-21-6 thiophosphoric acid S-(1-benzyl-1-methyl-2-oxo-2-phenyethyl) ester O,O-diethyl ester 
• 7302-06-9 (2-methylprop-1-ene-1,3-diyl)dibenzene 
• 7302-06-9 (E)-(2-methylprop-1-ene-1,3-diyl)dibenzene 
• 119244-56-3 1,3-diphenyl-1-<(trimethylsilyl)oxy>-2-methyl-1-propene 
• 38857-84-0 (1R₂R,1S₂S)-2-methyl-1,3-diphenylpropan-1-ol 
• 38857-84-0 (1R₂S,1S₂R)-2-methyl-1,3-diphenylpropan-1-ol 
• 35099-60-6 2-methyl-3-phenylindene 
• 860763-69-5 2-benzyl-2-methyl-1-phenyl-pent-4-en-1-one 
• 13031-08-8 4-phenylpivalophenone 
• 861801-81-2 3-oxy-2-methyl-1.3-diphenyl-pentane 
• 94897-38-8 2-phenyl-3-benzyl-butanol-⁽²⁾ 
• 101518-61-0 2,2-dimethyl-3-phenylpropanamide 

Relevant articles and documents

Stereocontrol of Paterno-Buchi photocycloadditions

Diphenyloxetane was synthesized from photocycloaddition of benzaldehyde and styrene. The oxetane products, 2,3 trans and 2,3 cis isomers, were observed in a 3:1 ratio. Irradiation of 1-phenylpropene and trimethylsilyl cinnamyl ether under the same conditions also gave oxetanes. The silyl group resulted in high stereoselectivity for the oxetane formation.

Neutral-eosin Y-catalyzed regioselective hydroacylation of aryl alkenes under visible-light irradiation

Styrene derivatives were hydroacylated with exclusive anti-Markovnikov selectivity by using neutral eosin Y as a direct hydrogen-atom-transfer (HAT) catalyst under visible-light irradiation. Aldehydes and styrenes with various substituents were tolerated (>20 examples), giving the corresponding products in moderate to high yields. The key acyl radical intermediate was generated from a direct HAT process induced by photoexcited eosin Y. Subsequent addition to styrenes and a reverse HAT process generated the ketone products.

Chemoselective reduction of ?,￠-unsaturated carbonyl and carboxylic compounds by hydrogen iodide

The selective reduction of ?,￠-unsaturated carbonyl compounds was achieved to produce saturated carbonyl compounds with aqueous HI solution. The introduction of an aryl group at an ? or ￠ position efficiently facilitated the reduction with good yield. The reaction was applicable to compounds bearing carboxylic acids and halogen atoms. Through the investigation of the reaction mechanism, it was found that Michael-type addition of iodide occurred to produce ￠-iodo compounds followed by the reduction of C-I bond via anionic and radical paths.