485798-62-7

Basic information

• Product Name: tert-Butyl 4-cyclobutylpiperazine-1-carboxylate
• Synonyms: tert-Butyl 4-cyclobutylpiperazine-1-carboxylate
• CAS NO: 485798-62-7
• Molecular Formula: C₁₃H₂₄N₂O₂
• Molecular Weight: 240.35
• Mol File: 485798-62-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 315.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.090±0.06 g/cm3(Predicted)
• PKA: 7.52±0.70(Predicted)
• CAS DataBase Reference: tert-Butyl 4-cyclobutylpiperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 4-cyclobutylpiperazine-1-carboxylate(485798-62-7)
• EPA Substance Registry System: tert-Butyl 4-cyclobutylpiperazine-1-carboxylate(485798-62-7)

Safety Data

• Hazardous Substances Data: 485798-62-7(Hazardous Substances Data)

Upstream product

• 2919-23-5 cyclobutanol 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 27374-25-0 [(1-Ethoxycyclopropyl)oxy]trimethylsilane 
• 1191-95-3 cyclobutanone 

Downstream Products

• 1035271-09-0 ethyl 4-(4-cyclobutylpiperazin-1-yl)benzoate 
• 1000405-21-9 4-(4-cyclobutylpiperazine-1-carbonyl)benzaldehyde 
• 132800-13-6 1-cyclobutyl-piperazine 

Relevant articles and documents

Pyrazolo [3,4 - the b] pyridine and [...] composition preparation method and use of (by machine translation)

The present invention provides a pyrazolo [3,4 - the b] pyridine and [...] compound of preparation and use, in particular, the present invention provides a following formula (I) compounds are shown, wherein the definition of each group as described in the specification. The compounds of the invention has excellent tyrosine kinase inhibiting activity, so can be used for preparing a series of treating diseases associated with the tyrosine kinase activity of the drug. (by machine translation)

MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS

The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.

Carbamate/urea derivatives

The invention relates to compound of the formula I or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it.