486460-19-9

Basic information

• Product Name: Carbamic acid, [(1R)-1-[(3,4-difluorophenyl)methyl]-3-(3-ethyl-5,6-dihydro-1,2,4-triazolo[ 4,3-a]pyrazin-7(8H)-yl)-3-oxopropyl]-, 1,1-dimethylethyl ester
• CAS NO: 486460-19-9
• Molecular Formula: C22H29F2N5O3
• Molecular Weight: 449.501
• Mol File: 486460-19-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [(1R)-1-[(3,4-difluorophenyl)methyl]-3-(3-ethyl-5,6-dihydro-1,2,4-triazolo[ 4,3-a]pyrazin-7(8H)-yl)-3-oxopropyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(1R)-1-[(3,4-difluorophenyl)methyl]-3-(3-ethyl-5,6-dihydro-1,2,4-triazolo[ 4,3-a]pyrazin-7(8H)-yl)-3-oxopropyl]-, 1,1-dimethylethyl ester(486460-19-9)
• EPA Substance Registry System: Carbamic acid, [(1R)-1-[(3,4-difluorophenyl)methyl]-3-(3-ethyl-5,6-dihydro-1,2,4-triazolo[ 4,3-a]pyrazin-7(8H)-yl)-3-oxopropyl]-, 1,1-dimethylethyl ester(486460-19-9)

Safety Data

• Hazardous Substances Data: 486460-19-9(Hazardous Substances Data)

Upstream product

• 140910-77-6 8-chloro-3-ethyl[1,2,4]triazolo[4,3-a]piperazine 
• 269396-59-0 (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(3,4-difluorophenyl)butanoic acid 

Relevant articles and documents

BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.