488713-30-0

Basic information

• Product Name: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-
• Synonyms: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-;3-Chloro-5-nitro-2-pyridinecarbonitrile;3-Chloro-5-nitropyridine-2-carbonitrile;3-Chloro-2-cyano-5-nitropyridine
• CAS NO: 488713-30-0
• Molecular Formula: C6H2ClN3O2
• Molecular Weight: 183.554
• Mol File: 488713-30-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-(488713-30-0)
• EPA Substance Registry System: 2-PYRIDINECARBONITRILE, 3-CHLORO-5-NITRO-(488713-30-0)

Safety Data

• Hazardous Substances Data: 488713-30-0(Hazardous Substances Data)

Usage

General Description

3-Chloro-5-nitro-2-pyridinecarbonitrile, also known as 3-chloro-5-nitropyridine-2-carbonitrile, is a chemical compound with the molecular formula C6H2ClN3O2. It belongs to the class of organic compounds known as nitropyridines, which are compounds containing a pyridine ring substituted at one or more positions by a nitro group. Its physical state is typically a liquid, and it may have a yellowish to brown color. As an organic compound, it is often primarily used in research and development, particularly in chemistry laboratories.

Upstream product

• 22353-40-8 2,3-dichloro-5-nitropyridine 
• 488713-29-7 3-chloro-2-iodo-5-nitropyridine 
• 1941-27-1 tetrabutylammonium nitrate 
• 38180-46-0 3-chloro-2-cyanopyridine 

Downstream Products

• 488713-31-1 5-amino-3-chloro-2-cyanopyridine 

Relevant articles and documents

HETEROCYCLIC COMPOUND

The problem of the present invention is to provide a compound having a superior RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like. The present invention relates to a compound represented by the formula (I): [wherein each symbol is as described in the DESCRIPTION] or a salt thereof, which has an RORγt inhibitory action, and useful as a prophylactic or therapeutic agent for psoriasis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, rheumatoid arthritis, multiple sclerosis, uveitis, asthma, ankylopoietic spondylarthritis, systemic lupus erythematosus, chronic obstructive pulmonary disease or the like.

Bicyclic modulators of androgen receptor function

The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula I wherein the substitutents are as described herein. Further provided are methods of using such compounds for the treatment of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia. Also provided are pharmaceutical compositions containing such compounds and processes for preparing some of the compounds of the invention.

2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS

The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.