4891-18-3

Basic information

• Product Name: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol
• Synonyms: Aids124349;Aids-124349;Methyl 2,3-anhydropentofuranoside;Nsc23609
• CAS NO: 4891-18-3
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.143
• Mol File: 4891-18-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 245.3 °C at 760 mmHg
• Flash Point: 102.2 °C
• Appearance: /
• Density: 1.33 g/cm³
• Vapor Pressure: 0.0048mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol(4891-18-3)
• EPA Substance Registry System: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol(4891-18-3)

Safety Data

• Hazardous Substances Data: 4891-18-3(Hazardous Substances Data)

Usage

Description

(2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol, also known as p-dioxane, is a bicyclic chemical compound that features an ether and alcohol functional group. It is widely recognized for its use as a solvent in various applications, particularly in the pharmaceutical industry and in the synthesis of organic compounds.

Uses

Used in Pharmaceutical Industry:
(2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol is used as a solvent for the production of pharmaceuticals due to its ability to dissolve a wide range of substances and facilitate chemical reactions.
Used in Organic Synthesis:
In the field of organic synthesis, (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol is used as a solvent to promote the formation of desired products and improve the efficiency of reactions.
While the compound is considered to have relatively low toxicity and is not classified as highly hazardous to human health or the environment, it is essential to adhere to proper handling and storage procedures to mitigate any potential risks associated with its use.

InChI:InChI=1/C6H10O4/c1-8-6-5-4(10-5)3(2-7)9-6/h3-7H,2H2,1H3

Upstream product

• 58-86-6 D-xylose 
• 79083-42-4 methyl D-arabinofuranoside 
• 1824-97-1 methyl β-D-xylofuranoside 
• 67-56-1 methanol 
• 124-41-4 sodium methylate 
• 109454-69-5 methyl-[O⁵-methoxycarbonyl-O³-(toluene-4-sulfonyl)-ξ-D-xylofuranoside 
• 110337-20-7 methyl-[O³-methanesulfonyl-O⁵-methoxycarbonyl-ξ-D-xylofuranoside 

Downstream Products

• 113091-75-1 methyl-[S-ethyl-bis-O-(4-nitro-benzoyl)-3-thio-β-D-xylofuranoside] 
• 119659-08-4 methyl-(S-ethyl-di-O-benzoyl-3-thio-β-D-xylofuranoside) 
• 143604-45-9 5-O-Benzyl-2-desoxy-2-dimethylamino-3-O-methanesulfonyl-β-D-arabinofuranoside de methyle 
• 143604-43-7 5-O-Benzyl-3-desoxy-3-dimethylamino-2-O-methanesulfonyl-β-D-xylofuranoside de methyle 
• 143604-54-0 5-O-Benzyl-2,3-didesoxy-3-dimethylamino-2-fluoro-β-D-xylofuranoside de methyle 
• 143604-36-8 5-O-Benzyl-3-desoxy-3-dimethylamino-β-D-xylofuranoside de methyle 
• 143604-55-1 5-O-Benzyl-2,3-didesoxy-2-dimethylamino-3-fluoro-β-D-arabinofuranoside de methyle 
• 143604-38-0 5-O-Benzyl-2-desoxy-2-dimethylamino-β-D-arabinofuranoside de methyle 
• 143604-32-4 2-Amino-5-O-benzyl-2-desoxy-β-D-arabinofuranoside de methyle 
• 60019-10-5 3-Amino-5-O-benzyl-3-desoxy-β-D-xylofuranoside de methyle 
• 143604-53-9 Methanesulfonate(1R,2S,4R,5S)-2-benzyloxymethyl-4-methoxy-6,6-dimethyl-3-oxa-6-azonia-bicyclo[3.1.0]hexane; 
• 143604-33-5 5-O-Benzyl-2-chloro-2,3-didesoxy-3-dimethylamino-β-D-xylofuranoside de methyle 
• 143604-34-6 5-O-Benzyl-3-chloro-2,3-didesoxy-2-dimethylamino-β-D-arabinofuranoside de methyle 
• 20535-09-5 2,3-Anhydro-5-O-benzyl-β-D-ribofuranoside de methyle 

Relevant articles and documents

Preparation of methyl 2,3-anhydro- and 2,3-o-sulfinylfuranosides from unprotected furanosides using the Mitsunobu reaction

A new two step procedure for the synthesis of methyl 2,3-anhydro-α-D-lyxofuranoside and methyl 2,3-anhydro-β-D-ribofuranoside from D-xylose involving the intramolecular Mitsunobu reaction is presented. Likewise, methyl 2,3-anhydro-α-L-lyxofuranoside is obtained from L-arabinose. Cyclic sulfites with D-ribo configuration, synthetic equivalents of the corresponding anhydrosugars, are prepared in three steps from D-ribose.